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Complexities of TGF-β Targeted Cancer Therapy

Many advanced tumors produce excessive amounts of Transforming Growth Factor-β (TGF-β) which, in normal epithelial cells, is a potent growth inhibitor. However, in oncogenically activated cells, the homeostatic action of TGF-β is often diverted along alternative pathways. Hence, TGF-β signaling elic...

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Bibliografske podrobnosti
Main Authors: Connolly, Erin C., Freimuth, Julia, Akhurst, Rosemary J.
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3399319/
https://ncbi.nlm.nih.gov/pubmed/22811618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.4564
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