Regulated proteolysis in microorganisms

par Dougan, David A.
Publié 2013

AAA+ Machines of Protein Destruction in Mycobacteria

par Thomas, Adam Atlas, Dougan, David A.
Publié dans Front Mol Biosci (2017)

MecA, an adaptor protein necessary for ClpC chaperone activity

par Schlothauer, Tilman, Mogk, Axel, Dougan, David A., Bukau, Bernd, Turgay, Kürşad
Publié 2003

The tyrosine kinase McsB is a regulated adaptor protein for ClpCP

par Kirstein, Janine, Dougan, David A, Gerth, Ulf, Hecker, Michael, Turgay, Kürşad
Publié 2007

Anti-adaptors use distinct modes of binding to inhibit the RssB-dependent turnover of RpoS (σ(S)) by ClpXP

par Micevski, Dimce, Zammit, Jessica E., Truscott, Kaye N., Dougan, David A.
Publié dans Front Mol Biosci (2015)

LON is the master protease that protects against protein aggregation in human mitochondria through direct degradation of misfolded proteins

par Bezawork-Geleta, Ayenachew, Brodie, Erica J., Dougan, David A., Truscott, Kaye N.
Publié dans Sci Rep (2015)

Perrault syndrome type 3 caused by diverse molecular defects in CLPP

par Brodie, Erica J., Zhan, Hanmiao, Saiyed, Tamanna, Truscott, Kaye N., Dougan, David A.
Publié dans Sci Rep (2018)

Crystal structure of bacterial succinate:quinone oxidoreductase flavoprotein SdhA in complex with its assembly factor SdhE

par Maher, Megan J., Herath, Anuradha S., Udagedara, Saumya R., Dougan, David A., Truscott, Kaye N.
Publié dans Proc Natl Acad Sci U S A (2018)

Modification of PATase by L/F-transferase generates a ClpS-dependent N-end rule substrate in Escherichia coli

par Ninnis, Robert L, Spall, Sukhdeep K, Talbo, Gert H, Truscott, Kaye N, Dougan, David A
Publié 2009

Adaptor protein controlled oligomerization activates the AAA+ protein ClpC

par Kirstein, Janine, Schlothauer, Tilman, Dougan, David A, Lilie, Hauke, Tischendorf, Gilbert, Mogk, Axel, Bukau, Bernd, Turgay, Kürşad
Publié 2006

Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS

par Schuenemann, Verena J, Kralik, Stephanie M, Albrecht, Reinhard, Spall, Sukhdeep K, Truscott, Kaye N, Dougan, David A, Zeth, Kornelius
Publié 2009

Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS

par Schuenemann, Verena J, Kralik, Stephanie M, Albrecht, Reinhard, Spall, Sukhdeep K, Truscott, Kaye N, Dougan, David A, Zeth, Kornelius
Publié 2009

Molecular and structural insights into an asymmetric proteolytic complex (ClpP1P2) from Mycobacterium smegmatis

par Nagpal, Jyotsna, Paxman, Jason J., Zammit, Jessica E., Thomas, Adam A., Truscott, Kaye N., Heras, Begoña, Dougan, David A.
Publié dans Sci Rep (2019)

Insight into the RssB-Mediated Recognition and Delivery of σ(s) to the AAA+ Protease, ClpXP

par Micevski, Dimce, Zeth, Kornelius, Mulhern, Terrence D., Schuenemann, Verena J., Zammit, Jessica E., Truscott, Kaye N., Dougan, David A.
Publié dans Biomolecules (2020)

Polymerase delta-interacting protein 38 (PDIP38) modulates the stability and activity of the mitochondrial AAA+ protease CLPXP

par Strack, Philip R., Brodie, Erica J., Zhan, Hanmiao, Schuenemann, Verena J., Valente, Liz J., Saiyed, Tamanna, Lowth, Bradley R., Angley, Lauren M., Perugini, Matthew A., Zeth, Kornelius, Truscott, Kaye N., Dougan, David A.
Publié dans Commun Biol (2020)