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Modification of PATase by L/F-transferase generates a ClpS-dependent N-end rule substrate in Escherichia coli
The N-end rule pathway is conserved from bacteria to man and determines the half-life of a protein based on its N-terminal amino acid. In Escherichia coli, model substrates bearing an N-degron are recognised by ClpS and degraded by ClpAP in an ATP-dependent manner. Here, we report the isolation of 2...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699360/ https://ncbi.nlm.nih.gov/pubmed/19440203 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.134 |
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