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ClpS modulates but is not essential for bacterial N-end rule degradation

In eubacteria, the ClpS adaptor has been proposed to be essential for degradation of N-end rule substrates by the AAA(+) protease ClpAP. To test this model, we assayed degradation of substrates bearing N-end rule sequences isolated in a genetic screen for efficient degradation tags. ClpS was not vit...

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Autors principals: Wang, Kevin H., Sauer, Robert T., Baker, Tania A.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1804329/
https://ncbi.nlm.nih.gov/pubmed/17322400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1511907
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