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Structural basis of N-end rule substrate recognition in Escherichia coli by the ClpAP adaptor protein ClpS

In Escherichia coli, the ClpAP protease, together with the adaptor protein ClpS, is responsible for the degradation of proteins bearing an amino-terminal destabilizing amino acid (N-degron). Here, we determined the three-dimensional structures of ClpS in complex with three peptides, each having a di...

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Detalhes bibliográficos
Main Authors: Schuenemann, Verena J, Kralik, Stephanie M, Albrecht, Reinhard, Spall, Sukhdeep K, Truscott, Kaye N, Dougan, David A, Zeth, Kornelius
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680879/
https://ncbi.nlm.nih.gov/pubmed/19373253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2009.62
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