Sirtuin biology and relevance to diabetes treatment

Por Dong, X Charlie
Publicado em 2012

The Potential of Sestrins as Therapeutic Targets for Diabetes

Por Dong, X. Charlie
Publicado no Expert Opin Ther Targets (2015)

SCP4: A Small Nuclear Phosphatase Having a Big Effect on FoxOs in Gluconeogenesis

Por Dong, X. Charlie
Publicado no Diabetes (2018)

FOXO transcription factors in non-alcoholic fatty liver disease

Por Dong, X. Charlie
Publicado no Liver Res (2017)

A closer look at the mysterious HSD17B13(1)

Por Dong, X. Charlie
Publicado no J Lipid Res (2020)

Sestrin 3 Protein Enhances Hepatic Insulin Sensitivity by Direct Activation of the mTORC2-Akt Signaling

Por Tao, Rongya, Xiong, Xiwen, Liangpunsakul, Suthat, Dong, X. Charlie
Publicado no Diabetes (2015)

The Autophagy-related Gene 14 (Atg14) Is Regulated by Forkhead Box O Transcription Factors and Circadian Rhythms and Plays a Critical Role in Hepatic Autophagy and Lipid Metabolism

Por Xiong, Xiwen, Tao, Rongya, DePinho, Ronald A., Dong, X. Charlie
Publicado em 2012

Deletion of Hepatic FoxO1/3/4 Genes in Mice Significantly Impacts on Glucose Metabolism through Downregulation of Gluconeogenesis and Upregulation of Glycolysis

Por Xiong, Xiwen, Tao, Rongya, DePinho, Ronald A., Dong, X. Charlie
Publicado em 2013

Irs2 and Irs4 synergize in non-LepRb neurons to control energy balance and glucose homeostasis()

Por Sadagurski, Marianna, Dong, X. Charlie, Myers, Martin G., White, Morris F.
Publicado em 2013

Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1

Por Wei, Dan, Tao, Rongya, Zhang, Yao, White, Morris F., Dong, X. Charlie
Publicado em 2011

FOXO transcription factors protect against the diet-induced fatty liver disease

Por Pan, Xiaoyan, Zhang, Yang, Kim, Hyeong-Geug, Liangpunsakul, Suthat, Dong, X. Charlie
Publicado no Sci Rep (2017)

The inhibitory effect of ethanol on Sestrin3 in the pathogenesis of ethanol-induced liver injury

Por Kang, Xinqin, Petyaykina, Kateryna, Tao, Rongya, Xiong, Xiwen, Dong, X. Charlie, Liangpunsakul, Suthat
Publicado em 2014

Fabp4-Cre-mediated Sirt6 deletion impairs adipose tissue function and metabolic homeostasis in mice

Por Xiong, Xiwen, Zhang, Cuicui, Zhang, Yang, Fan, Rui, Qian, Xinlai, Dong, X Charlie
Publicado no J Endocrinol (2017)

Hepatic SREBP-2 and cholesterol biosynthesis are regulated by FoxO3 and Sirt6

Por Tao, Rongya, Xiong, Xiwen, DePinho, Ronald A., Deng, Chu-Xia, Dong, X. Charlie
Publicado em 2013

FoxO3 Transcription Factor and Sirt6 Deacetylase Regulate Low Density Lipoprotein (LDL)-cholesterol Homeostasis via Control of the Proprotein Convertase Subtilisin/Kexin Type 9 (Pc...

Por Tao, Rongya, Xiong, Xiwen, DePinho, Ronald A., Deng, Chu-Xia, Dong, X. Charlie
Publicado em 2013

High fat diet rescues disturbances to metabolic homeostasis and survival in the Id2 null mouse in a sex-specific manner

Por Zhou, Peng, Hummel, Alyssa D., Pywell, Cameron M., Dong, X. Charlie, Duffield, Giles E.
Publicado no Biochem Biophys Res Commun (2014)

SliceIt: A genome-wide resource and visualization tool to design CRISPR/Cas9 screens for editing protein-RNA interaction sites in the human genome

Por Vemuri, Sasank, Srivastava, Rajneesh, Mir, Quoseena, Hashemikhabir, Seyedsasan, Dong, X. Charlie, Janga, Sarath Chandra
Publicado no Methods (2019)

Hepatic FoxOs Regulate Lipid Metabolism via Modulation of Expression of the Nicotinamide Phosphoribosyltransferase Gene

Por Tao, Rongya, Wei, Dan, Gao, Hanlin, Liu, Yunlong, DePinho, Ronald A., Dong, X. Charlie
Publicado em 2011

SIRT6 protects against palmitate-induced pancreatic β-cell dysfunction and apoptosis

Por Xiong, Xiwen, Sun, Xupeng, Wang, Qingzhi, Qian, Xinlai, Zhang, Yang, Pan, Xiaoyan, Dong, X. Charlie
Publicado no J Endocrinol (2016)

Prediction and Validation of Transcription Factors Modulating the Expression of Sestrin3 Gene Using an Integrated Computational and Experimental Approach

Por Srivastava, Rajneesh, Zhang, Yang, Xiong, Xiwen, Zhang, Xiaoning, Pan, Xiaoyan, Dong, X. Charlie, Liangpunsakul, Suthat, Janga, Sarath Chandra
Publicado no PLoS One (2016)