The β-isoform of BCCIP promotes ADP release from the RAD51 presynaptic filament and enhances homologous DNA pairing

por Kelso, Andrew A., Goodson, Steven D., Watts, Leah E., Ledford, LeAnna L., Waldvogel, Sarah M., Diehl, J. Nathaniel, Shah, Shivani B., Say, Amanda F., White, Julie D., Sehorn, Michael G.
Publicado en Nucleic Acids Res (2017)

The FBXO4 Tumor Suppressor Functions as a Barrier to Braf(V600E)-Dependent Metastatic Melanoma

por Lee, Eric K., Lian, Zhaorui, D'Andrea, Kurt, Letrero, Richard, Sheng, WeiQi, Liu, Shujing, Diehl, J. Nathaniel, Pytel, Dariusz, Barbash, Olena, Schuchter, Lynn, Amaravaradi, Ravi, Xu, Xiaowei, Herlyn, Meenhard, Nathanson, Katherine L., Diehl, J. Alan
Publicado 2013

Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer

por Zhang, Haisheng, Schaefer, Antje, Wang, Yichen, Hodge, Richard G., Blake, Devon R., Diehl, J. Nathaniel, Papageorge, Alex G., Stachler, Matthew, Liao, Jennifer, Zhou, Jin, Wu, Zhong, Akarca, Fahire, de Klerk, Leonie K., Derks, Sarah, Pierobon, Mariaelena, Hoadley, Katherine A., Wang, Timothy C., Church, George, Wong, Kwok-Kin, Petricoin, Emanuel F., Cox, Adrienne D., Lowy, Douglas R., Der, Channing J., Bass, Adam J.
Publicado en Cancer Discov (2019)

Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers

por Ozkan-Dagliyan, Irem, Diehl, J. Nathaniel, George, Samuel D., Schaefer, Antje, Papke, Bjoern, Klotz-Noack, Kathleen, Waters, Andrew M., Goodwin, Craig M., Gautam, Prson, Pierobon, Mariaelena, Peng, Sen, Gilbert, Thomas S.K., Lin, Kevin H., Dagliyan, Onur, Wennerberg, Krister, Petricoin, Emanuel F., Tran, Nhan L., Bhagwat, Shripad V., Tiu, Ramon V., Peng, Sheng-Bin, Herring, Laura E., Graves, Lee M., Sers, Christine, Wood, Kris C., Cox, Adrienne D., Der, Channing J.
Publicado en Cell Rep (2020)

Atypical KRAS(G12R) Mutant Is Impaired in PI3K Signaling and Macropinocytosis in Pancreatic Cancer

por Hobbs, G. Aaron, Baker, Nicole M., Miermont, Anne M., Thurman, Ryan D., Pierobon, Mariaelena, Tran, Timothy H., Anderson, Andrew O., Waters, Andrew M., Diehl, J. Nathaniel, Papke, Bjoern, Hodge, Richard G., Klomp, Jennifer E., Goodwin, Craig M., DeLiberty, Jonathan M., Wang, Junning, Ng, Raymond W. S., Gautam, Prson, Bryant, Kirsten L., Esposito, Dominic, Campbell, Sharon L., Petricoin, Emanuel F., Simanshu, Dhirendra K., Aguirre, Andrew J., Wolpin, Brian M., Wennerberg, Krister, Rudloff, Udo, Cox, Adrienne D., Der, Channing J.
Publicado en Cancer Discov (2019)

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

por Bryant, Kirsten L., Stalnecker, Clint A., Zeitouni, Daniel, Klomp, Jennifer E., Peng, Sen, Tikunov, Andrey P., Gunda, Venugopal, Pierobon, Mariaelena, Waters, Andrew M., George, Samuel D., Tomar, Garima, Papke, Björn, Hobbs, G. Aaron, Yan, Liang, Hayes, Tikvah K., Diehl, J. Nathaniel, Goode, Gennifer D., Chaika, Nina V., Wang, Yingxue, Zhang, Guo-Fang, Witkiewicz, Agnieszka K., Knudsen, Erik S., Petricoin, Emanuel F., Singh, Pankaj K., Macdonald, Jeffrey M., Tran, Nhan L., Lyssiotis, Costas A., Ying, Haoqiang, Kimmelman, Alec C., Cox, Adrienne D., Der, Channing J.
Publicado en Nat Med (2019)