The β-isoform of BCCIP promotes ADP release from the RAD51 presynaptic filament and enhances homologous DNA pairing

Homologous recombination (HR) is a template-driven repair pathway that mends DNA double-stranded breaks (DSBs), and thus helps to maintain genome stability. The RAD51 recombinase facilitates DNA joint formation during HR, but to accomplish this task, RAD51 must be loaded onto the single-stranded DNA...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nucleic Acids Res
Egile Nagusiak: Kelso, Andrew A., Goodson, Steven D., Watts, Leah E., Ledford, LeAnna L., Waldvogel, Sarah M., Diehl, J. Nathaniel, Shah, Shivani B., Say, Amanda F., White, Julie D., Sehorn, Michael G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2017
Gaiak:
Genome Integrity, Repair and Replication
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314795/
https://ncbi.nlm.nih.gov/pubmed/27694622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw877
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