The β-isoform of BCCIP promotes ADP release from the RAD51 presynaptic filament and enhances homologous DNA pairing

Homologous recombination (HR) is a template-driven repair pathway that mends DNA double-stranded breaks (DSBs), and thus helps to maintain genome stability. The RAD51 recombinase facilitates DNA joint formation during HR, but to accomplish this task, RAD51 must be loaded onto the single-stranded DNA...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Kelso, Andrew A., Goodson, Steven D., Watts, Leah E., Ledford, LeAnna L., Waldvogel, Sarah M., Diehl, J. Nathaniel, Shah, Shivani B., Say, Amanda F., White, Julie D., Sehorn, Michael G.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Genome Integrity, Repair and Replication
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5314795/
https://ncbi.nlm.nih.gov/pubmed/27694622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw877
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