Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption

The SRS2 (Suppressor of RAD Six screen mutant 2) gene encodes an ATP-dependent DNA helicase that regulates homologous recombination in Saccharomyces cerevisiae. Mutations in SRS2 result in a hyper-recombination phenotype, sensitivity to DNA damaging agents and synthetic lethality with mutations that...

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Detalhes bibliográficos
Main Authors: Colavito, Sierra, Macris-Kiss, Margaret, Seong, Changhyun, Gleeson, Olive, Greene, Eric C., Klein, Hannah L., Krejci, Lumir, Sung, Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777448/
https://ncbi.nlm.nih.gov/pubmed/19745052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp748
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