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Rad52-Rad51 association is essential to protect Rad51 filaments against Srs2, but facultative for filament formation

Homology search and strand exchange mediated by Rad51 nucleoprotein filaments are key steps of the homologous recombination process. In budding yeast, Rad52 is the main mediator of Rad51 filament formation, thereby playing an essential role. The current model assumes that Rad51 filament formation re...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ma, Emilie, Dupaigne, Pauline, Maloisel, Laurent, Guerois, Raphaël, Le Cam, Eric, Coïc, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6056232/
https://ncbi.nlm.nih.gov/pubmed/29985128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.32744
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