Rad52 Sumoylation Prevents the Toxicity of Unproductive Rad51 Filaments Independently of the Anti-Recombinase Srs2

The budding yeast Srs2 is the archetype of helicases that regulate several aspects of homologous recombination (HR) to maintain genomic stability. Srs2 inhibits HR at replication forks and prevents high frequencies of crossing-over. Additionally, sensitivity to DNA damage and synthetic lethality wit...

Полное описание

Сохранить в:
Библиографические подробности
Главные авторы: Esta, Aline, Ma, Emilie, Dupaigne, Pauline, Maloisel, Laurent, Guerois, Raphaël, Le Cam, Eric, Veaute, Xavier, Coïc, Eric
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2013
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3794917/
https://ncbi.nlm.nih.gov/pubmed/24130504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1003833
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы