Translational readthrough by the aminoglycoside geneticin (G418) modulates SMN stability in vitro and improves motor function in SMA mice in vivo

Por Heier, Christopher R., DiDonato, Christine J.
Publicado em 2009

ECG in neonate mice with spinal muscular atrophy allows assessment of drug efficacy

Por Heier, Christopher R., DiDonato, Christine J.
Publicado no Front Biosci (Elite Ed) (2015)

Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice

Por Heier, Christopher R., Satta, Rosalba, Lutz, Cathleen, DiDonato, Christine J.
Publicado em 2010

Molecular and phenotypic reassessment of an infrequently used mouse model for spinal muscular atrophy

Por Gogliotti, Rocky G., Hammond, Suzan M., Lutz, Cathleen, DiDonato, Christine J.
Publicado em 2009

Development of electrocardiogram intervals during growth of FVB/N neonate mice

Por Heier, Christopher R, Hampton, Thomas G, Wang, Deli, DiDonato, Christine J
Publicado em 2010

Antisense oligonucleotide mediated therapy of spinal muscular atrophy

Por Sivanesan, Senthilkumar, Howell, Matthew D., DiDonato, Christine J., Singh, Ravindra N.
Publicado em 2013

Mechanistic principles of antisense targets for the treatment of Spinal Muscular Atrophy

Por Singh, Natalia N., Lee, Brian M., DiDonato, Christine J., Singh, Ravindra N.
Publicado no Future Med Chem (2015)

Characterization of a commonly used mouse model of SMA reveals increased seizure susceptibility and heightened fear response in FVB/N mice

Por Gogliotti, Rocky G., Lutz, Cathleen, Jorgensen, Michael, Huebsch, Kimberly, Koh, Sookyong, DiDonato, Christine J.
Publicado em 2011

Mouse Survival Motor Neuron Alleles That Mimic SMN2 Splicing and Are Inducible Rescue Embryonic Lethality Early in Development but Not Late

Por Hammond, Suzan M., Gogliotti, Rocky G., Rao, Vamshi, Beauvais, Ariane, Kothary, Rashmi, DiDonato, Christine J.
Publicado em 2010

A Short Antisense Oligonucleotide Ameliorates Symptoms of Severe Mouse Models of Spinal Muscular Atrophy

Por Keil, Jeffrey M, Seo, Joonbae, Howell, Matthew D, Hsu, Walter H, Singh, Ravindra N, DiDonato, Christine J
Publicado em 2014

Motor Neuron Rescue in Spinal Muscular Atrophy Mice Demonstrates That Sensory-Motor Defects Are a Consequence, Not a Cause, of Motor Neuron Dysfunction

Por Gogliotti, Rocky G., Quinlan, Katharina A., Barlow, Courtenay B., Heier, Christopher R., Heckman, C. J., DiDonato, Christine J.
Publicado em 2012

Dissociation of hepatic insulin resistance from susceptibility of nonalcoholic fatty liver disease induced by a high-fat and high-carbohydrate diet in mice

Por Asai, Akihiro, Chou, Pauline M., Bu, Heng-Fu, Wang, Xiao, Rao, M. Sambasiva, Jiang, Anthony, DiDonato, Christine J., Tan, Xiao-Di
Publicado em 2014

Neuronal SMN expression corrects spinal muscular atrophy in severe SMA mice while muscle-specific SMN expression has no phenotypic effect

Por Gavrilina, Tatiana O., McGovern, Vicki L., Workman, Eileen, Crawford, Thomas O., Gogliotti, Rocky G., DiDonato, Christine J., Monani, Umrao R., Morris, Glenn E., Burghes, Arthur H.M.
Publicado em 2008

Absence of UCHL 1 function leads to selective motor neuropathy

Por Genç, Barış, Jara, Javier H., Schultz, Megan C., Manuel, Marin, Stanford, Macdonell J., Gautam, Mukesh, Klessner, Jodi L., Sekerkova, Gabriella, Heller, Daniel B., Cox, Gregory A., Heckman, Charles J., DiDonato, Christine J., Özdinler, P. Hande
Publicado no Ann Clin Transl Neurol (2016)

Association between Ag1-CA Alleles and Severity of Autosomal Recessive Proximal Spinal Muscular Atrophy

Por DiDonato, Christine J., Morgan, Kenneth, Carpten, John D., Fuerst, Paul, Ingraham, Susan E., Prescott, Gary, McPherson, John D., Wirth, Brunhilde, Zerres, Klaus, Hurko, Orest, Wasmuth, John J., Mendell, Jerry R., Burghes, Arthur H. M., Simard, Louise R.
Publicado em 1994

The DcpS inhibitor RG3039 improves survival, function and motor unit pathologies in two SMA mouse models

Por Gogliotti, Rocky G., Cardona, Herminio, Singh, Jasbir, Bail, Sophie, Emery, Carina, Kuntz, Nancy, Jorgensen, Michael, Durens, Madel, Xia, Bing, Barlow, Courtenay, Heier, Christopher R., Plasterer, Heather L., Jacques, Vincent, Kiledjian, Megerditch, Jarecki, Jill, Rusche, James, DiDonato, Christine J.
Publicado em 2013

In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels

Por Cherry, Jonathan J., DiDonato, Christine J., Androphy, Elliot J., Calo, Alessandro, Potter, Kyle, Custer, Sara K., Du, Sarah, Foley, Timothy L., Gopalsamy, Ariamala, Reedich, Emily J., Gordo, Susana M., Gordon, William, Hosea, Natalie, Jones, Lyn H., Krizay, Daniel K., LaRosa, Gregory, Li, Hongxia, Mathur, Sachin, Menard, Carol A., Patel, Paraj, Ramos-Zayas, Rebeca, Rietz, Anne, Rong, Haojing, Zhang, Baohong, Tones, Michael A.
Publicado no PLoS One (2017)