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Arrhythmia and cardiac defects are a feature of spinal muscular atrophy model mice

Proximal spinal muscular atrophy (SMA) is the leading genetic cause of infant mortality. Traditionally, SMA has been described as a motor neuron disease; however, there is a growing body of evidence that arrhythmia and/or cardiomyopathy may present in SMA patients at an increased frequency. Here, we...

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Главные авторы: Heier, Christopher R., Satta, Rosalba, Lutz, Cathleen, DiDonato, Christine J.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2010
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2947406/
https://ncbi.nlm.nih.gov/pubmed/20693262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq330
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