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Inhibition of myostatin does not ameliorate disease features of severe spinal muscular atrophy mice
There is currently no treatment for the inherited motor neuron disease, spinal muscular atrophy (SMA). Severe SMA causes lower motor neuron loss, impaired myofiber development, profound muscle weakness and early mortality. Myostatin is a transforming growth factor-β family member that inhibits muscl...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2733819/ https://ncbi.nlm.nih.gov/pubmed/19477958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp253 |
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