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Astrocytes influence the severity of spinal muscular atrophy
Systemically low levels of survival motor neuron-1 (SMN1) protein cause spinal muscular atrophy (SMA). α-Motor neurons of the spinal cord are considered particularly vulnerable in this genetic disorder and their dysfunction and loss cause progressive muscle weakness, paralysis and eventually prematu...
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| 出版年: | Hum Mol Genet |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5007659/ https://ncbi.nlm.nih.gov/pubmed/25911676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv148 |
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