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Defects in Motoneuron–Astrocyte Interactions in Spinal Muscular Atrophy
Spinal muscular atrophy (SMA) is a motoneuron disease caused by loss or mutation in Survival of Motor Neuron 1 (SMN1) gene. Recent studies have shown that selective restoration of SMN protein in astrocytes partially alleviates pathology in an SMA mouse model, suggesting important roles for astrocyte...
Shranjeno v:
| izdano v: | J Neurosci |
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| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6705489/ https://ncbi.nlm.nih.gov/pubmed/26911699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3534-15.2016 |
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