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Severe neuromuscular denervation of clinically relevant muscles in a mouse model of spinal muscular atrophy
Spinal muscular atrophy (SMA), a motoneuron disease caused by a deficiency of the survival of motor neuron (SMN) protein, is characterized by motoneuron loss and muscle weakness. It remains unclear whether widespread loss of neuromuscular junctions (NMJs) is involved in SMA pathogenesis. We undertoo...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3235013/ https://ncbi.nlm.nih.gov/pubmed/21968514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr453 |
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