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Defects in Motoneuron–Astrocyte Interactions in Spinal Muscular Atrophy

Spinal muscular atrophy (SMA) is a motoneuron disease caused by loss or mutation in Survival of Motor Neuron 1 (SMN1) gene. Recent studies have shown that selective restoration of SMN protein in astrocytes partially alleviates pathology in an SMA mouse model, suggesting important roles for astrocyte...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Zhou, Chunyi, Feng, Zhihua, Ko, Chien-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6705489/
https://ncbi.nlm.nih.gov/pubmed/26911699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3534-15.2016
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