Restoration of SMN to Emx-1 expressing cortical neurons is not sufficient to provide benefit to a severe mouse model of Spinal Muscular Atrophy

Por Taylor, Alexander S., Glascock, Jacqueline J., Rose, Ferrill F., Lutz, Cathleen, Lorson, Christian L.
Publicado em 2013

Direct central nervous system delivery provides enhanced protection following vector mediated gene replacement in a severe model of Spinal Muscular Atrophy

Por Glascock, Jacqueline J., Shababi, Monir, Wetz, Mary J., Krogman, Megan M., Lorson, Christian L.
Publicado em 2011

Defining the therapeutic window in a severe animal model of spinal muscular atrophy

Por Robbins, Kate L., Glascock, Jacqueline J., Osman, Erkan Y., Miller, Madeline R., Lorson, Christian L.
Publicado em 2014

Delivery of Therapeutic Agents Through Intracerebroventricular (ICV) and Intravenous (IV) Injection in Mice

Por Glascock, Jacqueline J., Osman, Erkan Y., Coady, Tristan H., Rose, Ferrill F., Shababi, Monir, Lorson, Christian L.
Publicado em 2011

Decreasing Disease Severity in Symptomatic, Smn(−/−);SMN2(+/+), Spinal Muscular Atrophy Mice Following scAAV9-SMN Delivery

Por Glascock, Jacqueline J., Osman, Erkan Y., Wetz, Mary J., Krogman, Megan M., Shababi, Monir, Lorson, Christian L.
Publicado em 2012

Plastin-3 extends survival and reduces severity in mouse models of spinal muscular atrophy

Por Kaifer, Kevin A., Villalón, Eric, Osman, Erkan Y., Glascock, Jacqueline J., Arnold, Laura L., Cornelison, D.D.W., Lorson, Christian L.
Publicado no JCI Insight (2017)

Astrocytes influence the severity of spinal muscular atrophy

Por Rindt, Hansjörg, Feng, Zhihua, Mazzasette, Chiara, Glascock, Jacqueline J., Valdivia, David, Pyles, Noah, Crawford, Thomas O., Swoboda, Kathryn J., Patitucci, Teresa N., Ebert, Allison D., Sumner, Charlotte J., Ko, Chien-Ping, Lorson, Christian L.
Publicado no Hum Mol Genet (2015)