Resonance assignments of an α-synuclein fibril prepared in Tris buffer at moderate ionic strength

door Barclay, Alexander M., Dhavale, Dhruva D., Courtney, Joseph M., Kotzbauer, Paul T., Rienstra, Chad M.
Gepubliceerd in Biomol NMR Assign (2018)

A sensitive assay reveals structural requirements for α-synuclein fibril growth

door Dhavale, Dhruva D., Tsai, Christina, Bagchi, Devika P., Engel, Laura A., Sarezky, Jonathan, Kotzbauer, Paul T.
Gepubliceerd in J Biol Chem (2017)

Design, synthesis, and in vitro evaluation of quinolinyl analogues for α-synuclein aggregation

door Yue, Xuyi, Dhavale, Dhruva D., Li, Junfeng, Luo, Zonghua, Liu, Jialu, Yang, Hao, Mach, Robert H., Kotzbauer, Paul T., Tu, Zhude
Gepubliceerd in Bioorg Med Chem Lett (2018)

Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation

door French, Rachel L., Grese, Zachary R., Aligireddy, Himani, Dhavale, Dhruva D., Reeb, Ashley N., Kedia, Niraja, Kotzbauer, Paul T., Bieschke, Jan, Ayala, Yuna M.
Gepubliceerd in J Biol Chem (2019)

Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics

door Yamasaki, Tritia R., Holmes, Brandon B., Furman, Jennifer L., Dhavale, Dhruva D., Su, Bryant W., Song, Eun-Suk, Cairns, Nigel J., Kotzbauer, Paul T., Diamond, Marc I.
Gepubliceerd in J Biol Chem (2019)

Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aβ) in Alzheimer’s Disease

door Sundaram, G. S. M., Dhavale, Dhruva D., Prior, Julie L., Yan, Ping, Cirrito, John, Rath, Nigam P., Laforest, Richard, Cairns, Nigel J., Lee, Jin-Moo, Kotzbauer, Paul T., Sharma, Vijay
Gepubliceerd in Sci Rep (2016)

APOE Genotype Regulates Pathology and Disease Progression in Synucleinopathy

door Davis, Albert A., Inman, Casey E., Wargel, Zachary M., Dube, Umber, Freeberg, Brittany M., Galluppi, Alexander, Haines, Jessica N., Dhavale, Dhruva D., Miller, Rebecca, Choudhury, Fahim A., Sullivan, Patrick M., Cruchaga, Carlos, Perlmutter, Joel S., Ulrich, Jason D., Benitez, Bruno A., Kotzbauer, Paul T., Holtzman, David M.
Gepubliceerd in Sci Transl Med (2020)