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Resonance assignments of an α-synuclein fibril prepared in Tris buffer at moderate ionic strength

Fibrils of the protein α-synuclein are implicated in the pathogenesis of Parkinson’s disease and related neurodegenerative disorders. We have reported a high-resolution structure (PDB 2N0A) of an α-synuclein fibril form prepared by in vitro incubation of monomeric protein in 50 mM sodium phosphate b...

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Dades bibliogràfiques
Publicat a:Biomol NMR Assign
Autors principals: Barclay, Alexander M., Dhavale, Dhruva D., Courtney, Joseph M., Kotzbauer, Paul T., Rienstra, Chad M.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5877819/
https://ncbi.nlm.nih.gov/pubmed/29476328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12104-018-9808-5
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