Resonance assignments of an α-synuclein fibril prepared in Tris buffer at moderate ionic strength

Por Barclay, Alexander M., Dhavale, Dhruva D., Courtney, Joseph M., Kotzbauer, Paul T., Rienstra, Chad M.
Publicado no Biomol NMR Assign (2018)

A sensitive assay reveals structural requirements for α-synuclein fibril growth

Por Dhavale, Dhruva D., Tsai, Christina, Bagchi, Devika P., Engel, Laura A., Sarezky, Jonathan, Kotzbauer, Paul T.
Publicado no J Biol Chem (2017)

Design, synthesis, and in vitro evaluation of quinolinyl analogues for α-synuclein aggregation

Por Yue, Xuyi, Dhavale, Dhruva D., Li, Junfeng, Luo, Zonghua, Liu, Jialu, Yang, Hao, Mach, Robert H., Kotzbauer, Paul T., Tu, Zhude
Publicado no Bioorg Med Chem Lett (2018)

Detection of TAR DNA-binding protein 43 (TDP-43) oligomers as initial intermediate species during aggregate formation

Por French, Rachel L., Grese, Zachary R., Aligireddy, Himani, Dhavale, Dhruva D., Reeb, Ashley N., Kedia, Niraja, Kotzbauer, Paul T., Bieschke, Jan, Ayala, Yuna M.
Publicado no J Biol Chem (2019)

Parkinson's disease and multiple system atrophy have distinct α-synuclein seed characteristics

Por Yamasaki, Tritia R., Holmes, Brandon B., Furman, Jennifer L., Dhavale, Dhruva D., Su, Bryant W., Song, Eun-Suk, Cairns, Nigel J., Kotzbauer, Paul T., Diamond, Marc I.
Publicado no J Biol Chem (2019)

Fluselenamyl: A Novel Benzoselenazole Derivative for PET Detection of Amyloid Plaques (Aβ) in Alzheimer’s Disease

Por Sundaram, G. S. M., Dhavale, Dhruva D., Prior, Julie L., Yan, Ping, Cirrito, John, Rath, Nigam P., Laforest, Richard, Cairns, Nigel J., Lee, Jin-Moo, Kotzbauer, Paul T., Sharma, Vijay
Publicado no Sci Rep (2016)

APOE Genotype Regulates Pathology and Disease Progression in Synucleinopathy

Por Davis, Albert A., Inman, Casey E., Wargel, Zachary M., Dube, Umber, Freeberg, Brittany M., Galluppi, Alexander, Haines, Jessica N., Dhavale, Dhruva D., Miller, Rebecca, Choudhury, Fahim A., Sullivan, Patrick M., Cruchaga, Carlos, Perlmutter, Joel S., Ulrich, Jason D., Benitez, Bruno A., Kotzbauer, Paul T., Holtzman, David M.
Publicado no Sci Transl Med (2020)