Role of Proprotein Convertases in Prostate Cancer Progression

Por Couture, Frédéric, D'Anjou, François, Desjardins, Roxane, Boudreau, François, Day, Robert
Publicado em 2012

An Unbiased Mass Spectrometry Approach Identifies Glypican-3 as an Interactor of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) and Low Density Lipoprotein Receptor (LDLR) i...

Por Ly, Kévin, Essalmani, Rachid, Desjardins, Roxane, Seidah, Nabil G., Day, Robert
Publicado no J Biol Chem (2016)

Proprotein Convertase 1/3 (PC1/3) in the Rat Alveolar Macrophage Cell Line NR8383: Localization, Trafficking and Effects on Cytokine Secretion

Por Gagnon, Hugo, Refaie, Sarah, Gagnon, Sandra, Desjardins, Roxane, Salzet, Michel, Day, Robert
Publicado em 2013

Strain-specific steroidal control of pituitary function

Por Lee, Sang-Nam, Peng, Bonnie, Desjardins, Roxane, Pintar, John E, Day, Robert, Lindberg, Iris
Publicado no J Endocrinol (2007)

PACE4 inhibitors and their peptidomimetic analogs block prostate cancer tumor progression through quiescence induction, increased apoptosis and impaired neovascularisation

Por Levesque, Christine, Couture, Frédéric, Kwiatkowska, Anna, Desjardins, Roxane, Guérin, Brigitte, Neugebauer, Witold A., Day, Robert
Publicado no Oncotarget (2015)

Multi-Leu PACE4 Inhibitor Retention within Cells Is PACE4 Dependent and a Prerequisite for Antiproliferative Activity

Por Couture, Frédéric, Ly, Kévin, Levesque, Christine, Kwiatkowska, Anna, Ait-Mohand, Samia, Desjardins, Roxane, Guérin, Brigitte, Day, Robert
Publicado no Biomed Res Int (2015)

Autocatalytic Activation of the Furin Zymogen Requires Removal of the Emerging Enzyme's N-Terminus from the Active Site

Por Gawlik, Katarzyna, Shiryaev, Sergey A., Zhu, Wenhong, Motamedchaboki, Khatereh, Desjardins, Roxane, Day, Robert, Remacle, Albert G., Stec, Boguslaw, Strongin, Alex Y.
Publicado em 2009

Implications of Proprotein Convertases in Ovarian Cancer Cell Proliferation and Tumor Progression: Insights for PACE4 as a Therapeutic Target()

Por Longuespée, Rémi, Couture, Frédéric, Levesque, Christine, Kwiatkowska, Anna, Desjardins, Roxane, Gagnon, Sandra, Vergara, Daniele, Maffia, Michelle, Fournier, Isabelle, Salzet, Michel, Day, Robert
Publicado em 2014

Annexin A2 Reduces PCSK9 Protein Levels via a Translational Mechanism and Interacts with the M1 and M2 Domains of PCSK9

Por Ly, Kévin, Luna Saavedra, Yascara Grisel, Canuel, Maryssa, Routhier, Sophie, Desjardins, Roxane, Hamelin, Josée, Mayne, Janice, Lazure, Claude, Seidah, Nabil G., Day, Robert
Publicado em 2014

Disruption of Proprotein Convertase 1/3 (PC1/3) Expression in Mice Causes Innate Immune Defects and Uncontrolled Cytokine Secretion

Por Refaie, Sarah, Gagnon, Sandra, Gagnon, Hugo, Desjardins, Roxane, D'Anjou, François, D'Orléans-Juste, Pedro, Zhu, Xiaorong, Steiner, Donald F., Seidah, Nabil G., Lazure, Claude, Salzet, Michel, Day, Robert
Publicado em 2012

Dissection of the Endogenous Cellular Pathways of PCSK9-induced Low Density Lipoprotein Receptor Degradation: EVIDENCE FOR AN INTRACELLULAR ROUTE

Por Poirier, Steve, Mayer, Gaetan, Poupon, Viviane, McPherson, Peter S., Desjardins, Roxane, Ly, Kevin, Asselin, Marie-Claude, Day, Robert, Duclos, Franck J., Witmer, Mark, Parker, Rex, Prat, Annik, Seidah, Nabil G.
Publicado em 2009

Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice

Por Wetsel, William C., Rodriguiz, Ramona M., Guillemot, Johann, Rousselet, Estelle, Essalmani, Rachid, Kim, Il Hwan, Bryant, Jesse C., Marcinkiewicz, Jadwiga, Desjardins, Roxane, Day, Robert, Constam, Daniel B., Prat, Annik, Seidah, Nabil G.
Publicado em 2013

Selective and potent furin inhibitors protect cells from anthrax without significant toxicity

Por Remacle, Albert G., Gawlik, Katarzyna, Golubkov, Vladislav S., Cadwell, Gregory W., Liddington, Robert C., Cieplak, Piotr, Millis, Sherri Z., Desjardins, Roxane, Routhier, Sophie, Yuan, Xue Wen, Neugebauer, Witold A., Day, Robert, Strongin, Alex Y.
Publicado em 2010

The Multi-Leu Peptide Inhibitor Discriminates Between PACE4 and Furin And Exhibits Antiproliferative Effects On Prostate Cancer Cells

Por Levesque, Christine, Fugère, Martin, Kwiatkowska, Anna, Couture, Frédéric, Desjardins, Roxane, Routhier, Sophie, Moussette, Philippe, Prahl, Adam, Lammek, Bernard, Appel, Jon R., Houghten, Richard A., D’Anjou, François, Dory, Yves L., Neugebauer, Witold, Day, Robert
Publicado em 2012

Substrate Cleavage Analysis of Furin and Related Proprotein Convertases: A COMPARATIVE STUDY

Por Remacle, Albert G., Shiryaev, Sergey A., Oh, Eok-Soo, Cieplak, Piotr, Srinivasan, Anupama, Wei, Ge, Liddington, Robert C., Ratnikov, Boris I., Parent, Amelie, Desjardins, Roxane, Day, Robert, Smith, Jeffrey W., Lebl, Michal, Strongin, Alex Y.
Publicado em 2008