Multi-Leu PACE4 Inhibitor Retention within Cells Is PACE4 Dependent and a Prerequisite for Antiproliferative Activity

The overexpression as well as the critical implication of the proprotein convertase PACE4 in prostate cancer progression has been previously reported and supported the development of peptide inhibitors. The multi-Leu peptide, a PACE4-specific inhibitor, was further generated and its capability to be...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Couture, Frédéric, Ly, Kévin, Levesque, Christine, Kwiatkowska, Anna, Ait-Mohand, Samia, Desjardins, Roxane, Guérin, Brigitte, Day, Robert
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465654/
https://ncbi.nlm.nih.gov/pubmed/26114115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/824014
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