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Multi-Leu PACE4 Inhibitor Retention within Cells Is PACE4 Dependent and a Prerequisite for Antiproliferative Activity

The overexpression as well as the critical implication of the proprotein convertase PACE4 in prostate cancer progression has been previously reported and supported the development of peptide inhibitors. The multi-Leu peptide, a PACE4-specific inhibitor, was further generated and its capability to be...

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Vydáno v:Biomed Res Int
Hlavní autoři: Couture, Frédéric, Ly, Kévin, Levesque, Christine, Kwiatkowska, Anna, Ait-Mohand, Samia, Desjardins, Roxane, Guérin, Brigitte, Day, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi Publishing Corporation 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465654/
https://ncbi.nlm.nih.gov/pubmed/26114115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/824014
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