Targeting inflammatory pathways for tumor radiosensitization

av Deorukhkar, Amit, Krishnan, Sunil
Publicerad 2010

Gadolinium Chloride Augments Tumor-Specific Imaging of Targeted Quantum Dots in vivo

av Diagaradjane, Parmeswaran, Deorukhkar, Amit, Gelovani, Juri G., Maru, Dipen M., Krishnan, Sunil
Publicerad 2010

Development and Validation of a Sensitive LC/MS/MS Method for the Determination of γ-Tocotrienol in Rat Plasma: Application to Pharmacokinetic Studies

av Liang, Su, Bian, Xiaomei, Ma, Jing, Arogunjo, Motolani, Deorukhkar, Amit A., Krishnan, Sunil, Xie, Huan
Publicerad 2012

Inhibition of radiation-induced DNA repair and pro-survival pathways contribute to vorinostat-mediated radiosensitization of pancreatic cancer cells

av Deorukhkar, Amit, Shujun, Shentu, Park, Hee Chul, Diagaradjane, Parmeswaran, Puduvalli, Vinay, Aggarwal, Bharat, Guha, Sushovan, Krishnan, Sunil
Publicerad 2010

Exploiting arginine auxotrophy with pegylated arginine deiminase (ADI-PEG20) to sensitize pancreatic cancer to radiotherapy via metabolic dysregulation

av Singh, Pankaj K., Deorukhkar, Amit A., Venkatesulu, Bhanu P., Li, Xiaolin, Tailor, Ramesh, Bomalaski, John S., Krishnan, Sunil
I publikationen Mol Cancer Ther (2019)

Integrin α(v)β(3)-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy

av Xie, Huan, Diagaradjane, Parmeswaran, Deorukhkar, Amit A, Goins, Beth, Bao, Ande, Phillips, William T, Wang, Zheng, Schwartz, Jon, Krishnan, Sunil
Publicerad 2011

Curcumin Modulates the Radiosensitivity of Colorectal Cancer Cells by Suppressing Constitutive and Inducible NF-κB Activity

av Sandur, Santosh K., Deorukhkar, Amit, Pandey, Manoj K., Pabón, Ana María, Shentu, Shujun, Guha, Sushovan, Aggarwal, Bharat B., Krishnan, Sunil
Publicerad 2009

Zerumbone increases oxidative stress in a thiol-dependent ROS-independent manner to increase DNA damage and sensitize colorectal cancer cells to radiation

av Deorukhkar, Amit, Ahuja, Niharika, Mercado, Armando-Lopez, Diagaradjane, Parmeswaran, Raju, Uma, Patel, Nalini, Mohindra, Pranshu, Diep, Nga, Guha, Sushovan, Krishnan, Sunil
I publikationen Cancer Med (2015)

Inhibition of EGFR or IGF-1R signaling enhances radiation response in head and neck cancer models but concurrent inhibition has no added benefit

av Raju, Uma, Molkentine, David P, Valdecanas, David R, Deorukhkar, Amit, Mason, Kathryn A, Buchholz, Thomas A, Meyn, Raymond E, Ang, Kie-Kian, Skinner, Heath
I publikationen Cancer Med (2015)

Ursolic Acid Inhibits Growth and Metastasis of Human Colorectal Cancer in an Orthotopic Nude Mouse Model by Targeting Multiple Cell Signaling Pathways: Chemosensitization with Cape...

av Prasad, Sahdeo, Yadav, Vivek R., Sung, Bokyung, Reuter, Simone, Kannappan, Ramaswamy, Deorukhkar, Amit, Diagaradjane, Parmeswaran, Wei, Caimiao, Baladandayuthapani, Veerabhadran, Krishnan, Sunil, Guha, Sushovan, Aggarwal, Bharat B.
Publicerad 2012

Zyflamend Suppresses Growth and Sensitizes Human Pancreatic Tumors to Gemcitabine in an Orthotopic Mouse Model Through Modulation of Multiple Targets

av Kunnumakkara, Ajaikumar B., Sung, Bokyung, Ravindran, Jayaraj, Diagaradjane, Parmeswaran, Deorukhkar, Amit, Dey, Sanjit, Koca, Cemile, Tong, Zhimin, Gelovani, Juri G., Guha, Sushovan, Krishnan, Sunil, Aggarwal, Bharat B.
Publicerad 2011

Hypoxia-targeted gold nanorods for cancer photothermal therapy

av Chen, Yuan, Bian, Xiaomei, Aliru, Maureen, Deorukhkar, Amit A., Ekpenyong, Oscar, Liang, Su, John, Jyothy, Ma, Jing, Gao, Xiuqing, Schwartz, Jon, Singh, Pankaj, Ye, Yuanqing, Krishnan, Sunil, Xie, Huan
I publikationen Oncotarget (2018)

γ-Tocotrienol Inhibits Pancreatic Tumors and Sensitizes Them to Gemcitabine Treatment by Modulating the Inflammatory Microenvironment

av Kunnumakkara, Ajaikumar B., Sung, Bokyung, Ravindran, Jayaraj, Diagaradjane, Parmeswaran, Deorukhkar, Amit, Dey, Sanjit, Koca, Cemile, Yadav, Vivek R., Tong, Zhimin, Gelovani, Juri G., Guha, Sushovan, Krishnan, Sunil, Aggarwal, Bharat B.
Publicerad 2010

Modulation of in Vivo Tumor Radiation Response via Gold Nanoshell-Mediated Vascular-Focused Hyperthermia: Characterizing an Integrated Antihypoxic and Localized Vascular Disrupting...

av Diagaradjane, Parmeswaran, Shetty, Anil, Wang, James C., Elliott, Andrew M., Schwartz, Jon, Shentu, Shujun, Park, Hee C., Deorukhkar, Amit, Stafford, R. Jason, Cho, Sang H., Tunnell, James W., Hazle, John D., Krishnan, Sunil
Publicerad 2008

Targeting of Pancreatic Cancer with Magneto-Fluorescent Theranostic Gold Nanoshells

av Chen, Wenxue, Ayala-Orozco, Ciceron, Biswal, Nrusingh C., Perez-Torres, Carlos, Bartels, Marc, Bardhan, Rizia, Stinnet, Gary, Liu, Xian-De, Ji, Baoan, Deorukhkar, Amit, Brown, Lisa V., Guha, Sushovan, Pautler, Robia G., Krishnan, Sunil, Halas, Naomi J, Joshi, Amit
Publicerad 2013

Mitochondrial fusion exploits a therapeutic vulnerability of pancreatic cancer

av Yu, Meifang, Nguyen, Nicholas D., Huang, Yanqing, Lin, Daniel, Fujimoto, Tara N., Molkentine, Jessica M., Deorukhkar, Amit, Kang, Ya’an, San Lucas, F. Anthony, Fernandes, Conrad J., Koay, Eugene J., Gupta, Sonal, Ying, Haoqiang, Koong, Albert C., Herman, Joseph M., Fleming, Jason B., Maitra, Anirban, Taniguchi, Cullen M.
I publikationen JCI Insight (2019)

Enteral Activation of WR-2721 Mediates Radioprotection and Improved Survival from Lethal Fractionated Radiation

av Molkentine, Jessica M., Fujimoto, Tara N., Horvath, Thomas D., Grossberg, Aaron J., Garcia, Carolina J. Garcia, Deorukhkar, Amit, de la Cruz Bonilla, Marimar, Lin, Daniel, Samuel, Errol L. G., Chan, Wai Kin, Lorenzi, Philip L., Piwnica-Worms, Helen, Dantzer, Robert, Tour, James M., Mason, Kathryn A., Taniguchi, Cullen M.
I publikationen Sci Rep (2019)

Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer

av Fujimoto, Tara N., Colbert, Lauren E., Huang, Yanqing, Molkentine, Jessica M., Deorukhkar, Amit, Baseler, Laura, de la Cruz Bonilla, Marimar, Yu, Meifang, Lin, Daniel, Gupta, Sonal, Cabeceiras, Peter K., Kingsley, Charles V., Tailor, Ramesh C., Sawakuchi, Gabriel O., Koay, Eugene J., Piwnica-Worms, Helen, Maitra, Anirban, Taniguchi, Cullen M.
I publikationen Cancer Res (2019)

A novel small molecule inhibitor of protein kinase D blocks pancreatic cancer growth in vitro and in vivo

av Harikumar, Kuzhuvelil B., Kunnumakkara, Ajaikumar B., Ochi, Nobuo, Tong, Zhimin, Deorukhkar, Amit, Sung, Bokyung, Kelland, Lloyd, Jamieson, Stephen, Sutherland, Rachel, Raynham, Tony, Charles, Mark, Bagherazadeh, Azadeh, Foxton, Caroline, Boakes, Alexandra, Farooq, Muddasar, Maru, Dipen, Diagaradjane, Parmeswaran, Matsuo, Yoichi, Sinnett-Smith, James, Gelovani, Juri, Krishnan, Sunil, Aggarwal, Bharat B., Rozengurt, Enrique, Ireson, Christopher R., Guha, Sushovan
Publicerad 2010