Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer

When pancreatic cancer cannot be removed surgically, patients frequently experience morbidity and death from progression of their primary tumor. Radiation therapy cannot yet substitute for an operation because radiation causes fatal bleeding and ulceration of the nearby stomach and intestines before...

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Veröffentlicht in:Cancer Res
Hauptverfasser: Fujimoto, Tara N., Colbert, Lauren E., Huang, Yanqing, Molkentine, Jessica M., Deorukhkar, Amit, Baseler, Laura, de la Cruz Bonilla, Marimar, Yu, Meifang, Lin, Daniel, Gupta, Sonal, Cabeceiras, Peter K., Kingsley, Charles V., Tailor, Ramesh C., Sawakuchi, Gabriel O., Koay, Eugene J., Piwnica-Worms, Helen, Maitra, Anirban, Taniguchi, Cullen M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6666414/
https://ncbi.nlm.nih.gov/pubmed/31043430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-1785
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