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Selective EGLN Inhibition Enables Ablative Radiotherapy and Improves Survival in Unresectable Pancreatic Cancer

When pancreatic cancer cannot be removed surgically, patients frequently experience morbidity and death from progression of their primary tumor. Radiation therapy cannot yet substitute for an operation because radiation causes fatal bleeding and ulceration of the nearby stomach and intestines before...

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Détails bibliographiques
Publié dans:Cancer Res
Auteurs principaux: Fujimoto, Tara N., Colbert, Lauren E., Huang, Yanqing, Molkentine, Jessica M., Deorukhkar, Amit, Baseler, Laura, de la Cruz Bonilla, Marimar, Yu, Meifang, Lin, Daniel, Gupta, Sonal, Cabeceiras, Peter K., Kingsley, Charles V., Tailor, Ramesh C., Sawakuchi, Gabriel O., Koay, Eugene J., Piwnica-Worms, Helen, Maitra, Anirban, Taniguchi, Cullen M.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6666414/
https://ncbi.nlm.nih.gov/pubmed/31043430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-18-1785
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