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Integrin α(v)β(3)-targeted gold nanoshells augment tumor vasculature-specific imaging and therapy

PURPOSE: Gold nanoshells (NSs) have already shown great promise as photothermal actuators for cancer therapy. Integrin α(v)β(3) is a marker that is specifically and preferentially overexpressed on multiple tumor types and on angiogenic tumor neovasculature. Active targeting of NSs to integrin α(v)β(...

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Detalhes bibliográficos
Main Authors: Xie, Huan, Diagaradjane, Parmeswaran, Deorukhkar, Amit A, Goins, Beth, Bao, Ande, Phillips, William T, Wang, Zheng, Schwartz, Jon, Krishnan, Sunil
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058535/
https://ncbi.nlm.nih.gov/pubmed/21423588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S15479
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