Caspase-7 uses RNA to enhance proteolysis of poly(ADP-ribose) polymerase 1 and other RNA-binding proteins

le Desroches, Alexandre, Denault, Jean-Bernard
Foilsithe in Proc Natl Acad Sci U S A (2019)

Caspase-7 uses an exosite to promote poly(ADP ribose) polymerase 1 proteolysis

le Boucher, Dave, Blais, Véronique, Denault, Jean-Bernard
Foilsithe 2012

Molecular determinants involved in activation of caspase 7

le BOUCHER, Dave, BLAIS, Véronique, DRAG, Marcin, DENAULT, Jean-Bernard
Foilsithe in Biosci Rep (2011)

Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)–mediated inhibition of caspase 9

le Denault, Jean-Bernard, Eckelman, Brendan P., Shin, Hwain, Pop, Cristina, Salvesen, Guy S.
Foilsithe 2007

Activation of caspases-8 and -10 by FLIP(L)

le Boatright, Kelly M., Deis, Cristina, Denault, Jean-Bernard, Sutherlin, Daniel P., Salvesen, Guy S.
Foilsithe 2004

XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs

le Scott, Fiona L, Denault, Jean-Bernard, Riedl, Stefan J, Shin, Hwain, Renatus, Martin, Salvesen, Guy S
Foilsithe 2005

Caspase-mediated proteolysis of the sorting nexin 2 disrupts retromer assembly and potentiates Met/hepatocyte growth factor receptor signaling

le Duclos, Catherine M, Champagne, Audrey, Carrier, Julie C, Saucier, Caroline, Lavoie, Christine L, Denault, Jean-Bernard
Foilsithe in Cell Death Discov (2017)

Caspases play in traffic

le Duclos, Catherine M, Champagne, Audrey, Carrier, Julie C, Saucier, Caroline, Lavoie, Christine L, Denault, Jean-Bernard
Foilsithe in Cell Death Dis (2017)

Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation

le Oberst, Andrew, Pop, Cristina, Tremblay, Alexandre G., Blais, Véronique, Denault, Jean-Bernard, Salvesen, Guy S., Green, Douglas R.
Foilsithe 2010

Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation.

le Oberst, Andrew, Pop, Cristina, Tremblay, Alexandre G., Blais, Véronique, Denault, Jean-Bernard, Salvesen, Guy S., Green, Douglas R.
Foilsithe 2014

Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function

le Scott, Fiona L., Fuchs, Greg J., Boyd, Sarah E., Denault, Jean-Bernard, Hawkins, Christine J., Dequiedt, Franck, Salvesen, Guy S.
Foilsithe 2008

NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity

le Gharagozloo, Marjan, Mahmoud, Shaimaa, Simard, Camille, Yamamoto, Kenzo, Bobbala, Diwakar, Ilangumaran, Subburaj, Smith, Matthew D., Lamontagne, Albert, Jarjoura, Samir, Denault, Jean-Bernard, Blais, Véronique, Gendron, Louis, Vilariño-Güell, Carles, Sadovnick, A. Dessa, Ting, Jenny P., Calabresi, Peter A., Amrani, Abdelaziz, Gris, Denis
Foilsithe in PLoS Biol (2019)