Caspase-7 uses RNA to enhance proteolysis of poly(ADP-ribose) polymerase 1 and other RNA-binding proteins

by Desroches, Alexandre, Denault, Jean-Bernard
Published in Proc Natl Acad Sci U S A (2019)

Caspase-7 uses an exosite to promote poly(ADP ribose) polymerase 1 proteolysis

by Boucher, Dave, Blais, Véronique, Denault, Jean-Bernard
Published 2012

Molecular determinants involved in activation of caspase 7

by BOUCHER, Dave, BLAIS, Véronique, DRAG, Marcin, DENAULT, Jean-Bernard
Published in Biosci Rep (2011)

Caspase 3 attenuates XIAP (X-linked inhibitor of apoptosis protein)–mediated inhibition of caspase 9

by Denault, Jean-Bernard, Eckelman, Brendan P., Shin, Hwain, Pop, Cristina, Salvesen, Guy S.
Published 2007

Activation of caspases-8 and -10 by FLIP(L)

by Boatright, Kelly M., Deis, Cristina, Denault, Jean-Bernard, Sutherlin, Daniel P., Salvesen, Guy S.
Published 2004

XIAP inhibits caspase-3 and -7 using two binding sites: evolutionarily conserved mechanism of IAPs

by Scott, Fiona L, Denault, Jean-Bernard, Riedl, Stefan J, Shin, Hwain, Renatus, Martin, Salvesen, Guy S
Published 2005

Caspase-mediated proteolysis of the sorting nexin 2 disrupts retromer assembly and potentiates Met/hepatocyte growth factor receptor signaling

by Duclos, Catherine M, Champagne, Audrey, Carrier, Julie C, Saucier, Caroline, Lavoie, Christine L, Denault, Jean-Bernard
Published in Cell Death Discov (2017)

Caspases play in traffic

by Duclos, Catherine M, Champagne, Audrey, Carrier, Julie C, Saucier, Caroline, Lavoie, Christine L, Denault, Jean-Bernard
Published in Cell Death Dis (2017)

Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation

by Oberst, Andrew, Pop, Cristina, Tremblay, Alexandre G., Blais, Véronique, Denault, Jean-Bernard, Salvesen, Guy S., Green, Douglas R.
Published 2010

Inducible dimerization and inducible cleavage reveal a requirement for both processes in caspase-8 activation.

by Oberst, Andrew, Pop, Cristina, Tremblay, Alexandre G., Blais, Véronique, Denault, Jean-Bernard, Salvesen, Guy S., Green, Douglas R.
Published 2014

Caspase-8 Cleaves Histone Deacetylase 7 and Abolishes Its Transcription Repressor Function

by Scott, Fiona L., Fuchs, Greg J., Boyd, Sarah E., Denault, Jean-Bernard, Hawkins, Christine J., Dequiedt, Franck, Salvesen, Guy S.
Published 2008

NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity

by Gharagozloo, Marjan, Mahmoud, Shaimaa, Simard, Camille, Yamamoto, Kenzo, Bobbala, Diwakar, Ilangumaran, Subburaj, Smith, Matthew D., Lamontagne, Albert, Jarjoura, Samir, Denault, Jean-Bernard, Blais, Véronique, Gendron, Louis, Vilariño-Güell, Carles, Sadovnick, A. Dessa, Ting, Jenny P., Calabresi, Peter A., Amrani, Abdelaziz, Gris, Denis
Published in PLoS Biol (2019)