Efficient Prioritization of Multiple Causal eQTL Variants via Sparse Polygenic Modeling

per Nariai, Naoki, Greenwald, William W., DeBoever, Christopher, Li, He, Frazer, Kelly A.
Publicat a Genetics (2017)

MiningABs: mining associated biomarkers across multi-connected gene expression datasets

per Cheng, Chun-Pei, DeBoever, Christopher, Frazer, Kelly A, Liu, Yu-Cheng, Tseng, Vincent S
Publicat 2014

Assessing Digital Phenotyping to Enhance Genetic Studies of Human Diseases

per DeBoever, Christopher, Tanigawa, Yosuke, Aguirre, Matthew, McInnes, Greg, Lavertu, Adam, Rivas, Manuel A.
Publicat a Am J Hum Genet (2020)

Context dependent substitution biases vary within the human genome

per Nevarez, P Andrew, DeBoever, Christopher M, Freeland, Benjamin J, Quitt, Marissa A, Bush, Eliot C
Publicat 2010

Systematic transcriptome analysis reveals tumor-specific isoforms for ovarian cancer diagnosis and therapy

per Barrett, Christian L., DeBoever, Christopher, Jepsen, Kristen, Saenz, Cheryl C., Carson, Dennis A., Frazer, Kelly A.
Publicat a Proc Natl Acad Sci U S A (2015)

Whole Transcriptome Sequencing Enables Discovery and Analysis of Viruses in Archived Primary Central Nervous System Lymphomas

per DeBoever, Christopher, Reid, Erin G., Smith, Erin N., Wang, Xiaoyun, Dumaop, Wilmar, Harismendy, Olivier, Carson, Dennis, Richman, Douglas, Masliah, Eliezer, Frazer, Kelly A.
Publicat 2013

Transcriptome Sequencing Reveals Potential Mechanism of Cryptic 3’ Splice Site Selection in SF3B1-mutated Cancers

per DeBoever, Christopher, Ghia, Emanuela M., Shepard, Peter J., Rassenti, Laura, Barrett, Christian L., Jepsen, Kristen, Jamieson, Catriona H. M., Carson, Dennis, Kipps, Thomas J., Frazer, Kelly A.
Publicat a PLoS Comput Biol (2015)

Medical relevance of protein-truncating variants across 337,205 individuals in the UK Biobank study

per DeBoever, Christopher, Tanigawa, Yosuke, Lindholm, Malene E., McInnes, Greg, Lavertu, Adam, Ingelsson, Erik, Chang, Chris, Ashley, Euan A., Bustamante, Carlos D., Daly, Mark J., Rivas, Manuel A.
Publicat a Nat Commun (2018)

Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology

per Tanigawa, Yosuke, Li, Jiehan, Justesen, Johanne M., Horn, Heiko, Aguirre, Matthew, DeBoever, Christopher, Chang, Chris, Narasimhan, Balasubramanian, Lage, Kasper, Hastie, Trevor, Park, Chong Y., Bejerano, Gill, Ingelsson, Erik, Rivas, Manuel A.
Publicat a Nat Commun (2019)

Discovery and quality analysis of a comprehensive set of structural variants and short tandem repeats

per Jakubosky, David, Smith, Erin N., D’Antonio, Matteo, Jan Bonder, Marc, Young Greenwald, William W., D’Antonio-Chronowska, Agnieszka, Matsui, Hiroko, Stegle, Oliver, Montgomery, Stephen B., DeBoever, Christopher, Frazer, Kelly A.
Publicat a Nat Commun (2020)

Distinct splicing signatures affect converged pathways in myelodysplastic syndrome patients carrying mutations in different splicing regulators

per Qiu, Jinsong, Zhou, Bing, Thol, Felicitas, Zhou, Yu, Chen, Liang, Shao, Changwei, DeBoever, Christopher, Hou, Jiayi, Li, Hairi, Chaturvedi, Anuhar, Ganser, Arnold, Bejar, Rafael, Zhang, Dong-Er, Fu, Xiang-Dong, Heuser, Michael
Publicat a RNA (2016)

Identifying DNase I hypersensitive sites as driver distal regulatory elements in breast cancer

per D′Antonio, Matteo, Weghorn, Donate, D′Antonio-Chronowska, Agnieszka, Coulet, Florence, Olson, Katrina M., DeBoever, Christopher, Drees, Frauke, Arias, Angelo, Alakus, Hakan, Richardson, Andrea L., Schwab, Richard B., Farley, Emma K., Sunyaev, Shamil R., Frazer, Kelly A
Publicat a Nat Commun (2017)

Properties of structural variants and short tandem repeats associated with gene expression and complex traits

per Jakubosky, David, D’Antonio, Matteo, Bonder, Marc Jan, Smail, Craig, Donovan, Margaret K. R., Young Greenwald, William W., Matsui, Hiroko, D’Antonio-Chronowska, Agnieszka, Stegle, Oliver, Smith, Erin N., Montgomery, Stephen B., DeBoever, Christopher, Frazer, Kelly A.
Publicat a Nat Commun (2020)

Interaction landscape of inherited polymorphisms with somatic events in cancer

per Carter, Hannah, Marty, Rachel, Hofree, Matan, Gross, Andy, Jensen, James, Fisch, Kathleen M., Wu, Xingyu, DeBoever, Christopher, Van Nostrand, Eric L, Song, Yan, Wheeler, Emily, Kreisberg, Jason F., Lippman, Scott M., Yeo, Gene, Gutkind, J. Silvio, Ideker, Trey
Publicat a Cancer Discov (2017)

High-level ROR1 associates with accelerated disease progression in chronic lymphocytic leukemia

per Cui, Bing, Ghia, Emanuela M., Chen, Liguang, Rassenti, Laura Z., DeBoever, Christopher, Widhopf, George F., Yu, Jian, Neuberg, Donna S., Wierda, William G., Rai, Kanti R., Kay, Neil E., Brown, Jennifer R., Jones, Jeffrey A., Gribben, John G., Frazer, Kelly A., Kipps, Thomas J.
Publicat a Blood (2016)

Large-Scale Profiling Reveals the Influence of Genetic Variation on Gene Expression in Human Induced Pluripotent Stem Cells

per DeBoever, Christopher, Li, He, Jakubosky, David, Benaglio, Paola, Reyna, Joaquin, Olson, Katrina M., Huang, Hui, Biggs, William, Sandoval, Efren, D’Antonio, Matteo, Jepsen, Kristen, Matsui, Hiroko, Arias, Angelo, Ren, Bing, Nariai, Naoki, Smith, Erin N., D’Antonio-Chronowska, Agnieszka, Farley, Emma K., Frazer, Kelly A.
Publicat a Cell Stem Cell (2017)

Allele-specific NKX2-5 binding underlies multiple genetic associations with human electrocardiographic traits

per Benaglio, Paola, D’Antonio-Chronowska, Agnieszka, Ma, Wubin, Yang, Feng, Young Greenwald, William W., Donovan, Margaret K. R., DeBoever, Christopher, Li, He, Drees, Frauke, Singhal, Sanghamitra, Matsui, Hiroko, van Setten, Jessica, Sotoodehnia, Nona, Gaulton, Kyle J., Smith, Erin N., D’Antonio, Matteo, Rosenfeld, Michael G., Frazer, Kelly A.
Publicat a Nat Genet (2019)

iPSCORE: A Resource of 222 iPSC Lines Enabling Functional Characterization of Genetic Variation across a Variety of Cell Types

per Panopoulos, Athanasia D., D'Antonio, Matteo, Benaglio, Paola, Williams, Roy, Hashem, Sherin I., Schuldt, Bernhard M., DeBoever, Christopher, Arias, Angelo D., Garcia, Melvin, Nelson, Bradley C., Harismendy, Olivier, Jakubosky, David A., Donovan, Margaret K.R., Greenwald, William W., Farnam, KathyJean, Cook, Megan, Borja, Victor, Miller, Carl A., Grinstein, Jonathan D., Drees, Frauke, Okubo, Jonathan, Diffenderfer, Kenneth E., Hishida, Yuriko, Modesto, Veronica, Dargitz, Carl T., Feiring, Rachel, Zhao, Chang, Aguirre, Aitor, McGarry, Thomas J., Matsui, Hiroko, Li, He, Reyna, Joaquin, Rao, Fangwen, O'Connor, Daniel T., Yeo, Gene W., Evans, Sylvia M., Chi, Neil C., Jepsen, Kristen, Nariai, Naoki, Müller, Franz-Josef, Goldstein, Lawrence S.B., Izpisua Belmonte, Juan Carlos, Adler, Eric, Loring, Jeanne F., Berggren, W. Travis, D'Antonio-Chronowska, Agnieszka, Smith, Erin N., Frazer, Kelly A.
Publicat a Stem Cell Reports (2017)