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Interaction landscape of inherited polymorphisms with somatic events in cancer

Recent studies have characterized the extensive somatic alterations that arise during cancer. However, the somatic evolution of a tumor may be significantly affected by inherited polymorphisms carried in the germline. Here, we analyze genomic data for 5954 tumors to reveal and systematically validat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cancer Discov
Egile Nagusiak: Carter, Hannah, Marty, Rachel, Hofree, Matan, Gross, Andy, Jensen, James, Fisch, Kathleen M., Wu, Xingyu, DeBoever, Christopher, Van Nostrand, Eric L, Song, Yan, Wheeler, Emily, Kreisberg, Jason F., Lippman, Scott M., Yeo, Gene, Gutkind, J. Silvio, Ideker, Trey
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5460679/
https://ncbi.nlm.nih.gov/pubmed/28188128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-16-1045
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