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Challenges in identifying cancer genes by analysis of exome sequencing data

Massively parallel sequencing has permitted an unprecedented examination of the cancer exome, leading to predictions that all genes important to cancer will soon be identified by genetic analysis of tumours. To examine this potential, here we evaluate the ability of state-of-the-art sequence analysi...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hofree, Matan, Carter, Hannah, Kreisberg, Jason F., Bandyopadhyay, Sourav, Mischel, Paul S., Friend, Stephen, Ideker, Trey
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947162/
https://ncbi.nlm.nih.gov/pubmed/27417679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12096
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