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Challenges in identifying cancer genes by analysis of exome sequencing data

Massively parallel sequencing has permitted an unprecedented examination of the cancer exome, leading to predictions that all genes important to cancer will soon be identified by genetic analysis of tumours. To examine this potential, here we evaluate the ability of state-of-the-art sequence analysi...

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Dades bibliogràfiques
Publicat a:Nat Commun
Autors principals: Hofree, Matan, Carter, Hannah, Kreisberg, Jason F., Bandyopadhyay, Sourav, Mischel, Paul S., Friend, Stephen, Ideker, Trey
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947162/
https://ncbi.nlm.nih.gov/pubmed/27417679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12096
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