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Challenges in identifying cancer genes by analysis of exome sequencing data

Massively parallel sequencing has permitted an unprecedented examination of the cancer exome, leading to predictions that all genes important to cancer will soon be identified by genetic analysis of tumours. To examine this potential, here we evaluate the ability of state-of-the-art sequence analysi...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Hofree, Matan, Carter, Hannah, Kreisberg, Jason F., Bandyopadhyay, Sourav, Mischel, Paul S., Friend, Stephen, Ideker, Trey
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4947162/
https://ncbi.nlm.nih.gov/pubmed/27417679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12096
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