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Efficient Prioritization of Multiple Causal eQTL Variants via Sparse Polygenic Modeling

Expression quantitative trait loci (eQTL) studies have typically used single-variant association analysis to identify genetic variants correlated with gene expression. However, this approach has several drawbacks: causal variants cannot be distinguished from nonfunctional variants in strong linkage...

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Detaylı Bibliyografya
Yayımlandı:Genetics
Asıl Yazarlar: Nariai, Naoki, Greenwald, William W., DeBoever, Christopher, Li, He, Frazer, Kelly A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5714449/
https://ncbi.nlm.nih.gov/pubmed/29074555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.300435
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