Hyperphosphorylation of the Hepatitis C Virus NS5A Protein Requires an Active NS3 Protease, NS4A, NS4B, and NS5A Encoded on the Same Polyprotein

Bằng Neddermann, Petra, Clementi, Angelica, De Francesco, Raffaele
Được phát hành 1999

Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides

Bằng Bressanelli, Stéphane, Tomei, Licia, Rey, Félix A., De Francesco, Raffaele
Được phát hành 2002

Selection of RNA Aptamers That Are Specific and High-Affinity Ligands of the Hepatitis C Virus RNA-Dependent RNA Polymerase

Bằng Biroccio, Antonino, Hamm, Jörg, Incitti, Ilario, De Francesco, Raffaele, Tomei, Licia
Được phát hành 2002

Naturally Occurring Hepatitis C Virus Subgenomic Deletion Mutants Replicate Efficiently in Huh-7 Cells and Are trans-Packaged In Vitro To Generate Infectious Defective Particles

Bằng Pacini, Laura, Graziani, Rita, Bartholomew, Linda, De Francesco, Raffaele, Paonessa, Giacomo
Được phát hành 2009

The α Isoform of Protein Kinase CKI Is Responsible for Hepatitis C Virus NS5A Hyperphosphorylation

Bằng Quintavalle, Manuela, Sambucini, Sonia, Di Pietro, Chiara, De Francesco, Raffaele, Neddermann, Petra
Được phát hành 2006

Mechanism of Hepatitis C Virus RNA Polymerase Inhibition with Dihydroxypyrimidines

Bằng Powdrill, Megan H., Deval, Jerome, Narjes, Frank, De Francesco, Raffaele, Götte, Matthias
Được phát hành 2010

Multiple Enzymatic Activities Associated with Recombinant NS3 Protein of Hepatitis C Virus

Bằng Gallinari, Paola, Brennan, Debra, Nardi, Chiara, Brunetti, Mirko, Tomei, Licia, Steinkühler, Christian, De Francesco, Raffaele
Được phát hành 1998

A novel, inducible, eukaryotic gene expression system based on the quorum-sensing transcription factor TraR

Bằng Neddermann, Petra, Gargioli, Cesare, Muraglia, Ester, Sambucini, Sonia, Bonelli, Fabio, De Francesco, Raffaele, Cortese, Riccardo
Được phát hành 2003

A novel, inducible, eukaryotic gene expression system based on the quorum-sensing transcription factor TraR (EMBO reports, February 2003) (Erratum)

Bằng Neddermann, Petra, Gargioli, Cesare, Muraglia, Ester, Sambucini, Sonia, Bonelli, Fabio, De Francesco, Raffaele, Cortese, Riccardo
Được phát hành 2003

Oxysterol-Binding Protein is a Phosphatidylinositol 4-kinase Effector Required for HCV Replication Membrane Integrity and Cholesterol Trafficking

Bằng WANG, HONGLIANG, PERRY, JEFFREY W., LAURING, ADAM S., NEDDERMANN, PETRA, DE FRANCESCO, RAFFAELE, TAI, ANDREW W.
Được phát hành 2014

The Enigmatic Role of Viruses in Multiple Sclerosis: Molecular Mimicry or Disturbed Immune Surveillance?

Bằng Geginat, Jens, Paroni, Moira, Pagani, Massimiliano, Galimberti, Daniela, De Francesco, Raffaele, Scarpini, Elio, Abrignani, Sergio
Xuất bản năm Trends Immunol (2017)

The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA

Bằng Vannini, Alessandro, Volpari, Cinzia, Gargioli, Cesare, Muraglia, Ester, Cortese, Riccardo, De Francesco, Raffaele, Neddermann, Petra, Di Marco, Stefania
Được phát hành 2002

Reduction of Hepatitis C Virus NS5A Hyperphosphorylation by Selective Inhibition of Cellular Kinases Activates Viral RNA Replication in Cell Culture

Bằng Neddermann, Petra, Quintavalle, Manuela, Di Pietro, Chiara, Clementi, Angelica, Cerretani, Mauro, Altamura, Sergio, Bartholomew, Linda, De Francesco, Raffaele
Được phát hành 2004

Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

Bằng Bressanelli, Stéphane, Tomei, Licia, Roussel, Alain, Incitti, Ilario, Vitale, Rosa Letizia, Mathieu, Magali, De Francesco, Raffaele, Rey, Félix A.
Được phát hành 1999

Selection of Functional Variants of the NS3-NS4A Protease of Hepatitis C Virus by Using Chimeric Sindbis Viruses

Bằng Filocamo, Gessica, Pacini, Laura, Nardi, Chiara, Bartholomew, Linda, Scaturro, Maria, Delmastro, Paola, Tramontano, Anna, De Francesco, Raffaele, Migliaccio, Giovanni
Được phát hành 1999

Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8–substrate complex

Bằng Vannini, Alessandro, Volpari, Cinzia, Gallinari, Paola, Jones, Philip, Mattu, Marco, Carfí, Andrea, De Francesco, Raffaele, Steinkühler, Christian, Di Marco, Stefania
Được phát hành 2007

Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity

Bằng Bianco, Annalisa, Reghellin, Veronica, Donnici, Lorena, Fenu, Simone, Alvarez, Reinaldo, Baruffa, Chiara, Peri, Francesco, Pagani, Massimiliano, Abrignani, Sergio, Neddermann, Petra, De Francesco, Raffaele
Được phát hành 2012

Cirrhosis and Rapid Virological Response to Peginterferon Plus Ribavirin Determine Treatment Outcome in HCV-1 IL28B rs12979860 CC Patients

Bằng Aghemo, Alessio, Degasperi, Elisabetta, Rumi, Maria Grazia, Galmozzi, Enrico, Valenti, Luca, De Francesco, Raffaele, De Nicola, Stella, Cheroni, Cristina, Grassi, Eleonora, Colombo, Massimo
Được phát hành 2013

NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains

Bằng Benzine, Tiffany, Brandt, Ryan, Lovell, William C., Yamane, Daisuke, Neddermann, Petra, De Francesco, Raffaele, Lemon, Stanley M., Perelson, Alan S., Ke, Ruian, McGivern, David R.
Xuất bản năm PLoS Pathog (2017)

In Vitro Selection and Characterization of Hepatitis C Virus Serine Protease Variants Resistant to an Active-Site Peptide Inhibitor

Bằng Trozzi, Caterina, Bartholomew, Linda, Ceccacci, Alessandra, Biasiol, Gabriella, Pacini, Laura, Altamura, Sergio, Narjes, Frank, Muraglia, Ester, Paonessa, Giacomo, Koch, Uwe, De Francesco, Raffaele, Steinkuhler, Christian, Migliaccio, Giovanni
Được phát hành 2003