Selection of Functional Variants of the NS3-NS4A Protease of Hepatitis C Virus by Using Chimeric Sindbis Viruses

The NS3-NS4A serine protease of hepatitis C virus (HCV) mediates four specific cleavages of the viral polyprotein and its activity is considered essential for the biogenesis of the HCV replication machinery. Despite extensive biochemical and structural characterization, the analysis of natural varia...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Filocamo, Gessica, Pacini, Laura, Nardi, Chiara, Bartholomew, Linda, Scaturro, Maria, Delmastro, Paola, Tramontano, Anna, De Francesco, Raffaele, Migliaccio, Giovanni
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1999
Assuntos:	Replication
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC103862/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9847361/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.73.1.561-575.1999
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!