Hyperphosphorylation of the Hepatitis C Virus NS5A Protein Requires an Active NS3 Protease, NS4A, NS4B, and NS5A Encoded on the Same Polyprotein

le Neddermann, Petra, Clementi, Angelica, De Francesco, Raffaele
Foilsithe 1999

Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides

le Bressanelli, Stéphane, Tomei, Licia, Rey, Félix A., De Francesco, Raffaele
Foilsithe 2002

Selection of RNA Aptamers That Are Specific and High-Affinity Ligands of the Hepatitis C Virus RNA-Dependent RNA Polymerase

le Biroccio, Antonino, Hamm, Jörg, Incitti, Ilario, De Francesco, Raffaele, Tomei, Licia
Foilsithe 2002

Naturally Occurring Hepatitis C Virus Subgenomic Deletion Mutants Replicate Efficiently in Huh-7 Cells and Are trans-Packaged In Vitro To Generate Infectious Defective Particles

le Pacini, Laura, Graziani, Rita, Bartholomew, Linda, De Francesco, Raffaele, Paonessa, Giacomo
Foilsithe 2009

The α Isoform of Protein Kinase CKI Is Responsible for Hepatitis C Virus NS5A Hyperphosphorylation

le Quintavalle, Manuela, Sambucini, Sonia, Di Pietro, Chiara, De Francesco, Raffaele, Neddermann, Petra
Foilsithe 2006

Mechanism of Hepatitis C Virus RNA Polymerase Inhibition with Dihydroxypyrimidines

le Powdrill, Megan H., Deval, Jerome, Narjes, Frank, De Francesco, Raffaele, Götte, Matthias
Foilsithe 2010

Multiple Enzymatic Activities Associated with Recombinant NS3 Protein of Hepatitis C Virus

le Gallinari, Paola, Brennan, Debra, Nardi, Chiara, Brunetti, Mirko, Tomei, Licia, Steinkühler, Christian, De Francesco, Raffaele
Foilsithe 1998

A novel, inducible, eukaryotic gene expression system based on the quorum-sensing transcription factor TraR

le Neddermann, Petra, Gargioli, Cesare, Muraglia, Ester, Sambucini, Sonia, Bonelli, Fabio, De Francesco, Raffaele, Cortese, Riccardo
Foilsithe 2003

A novel, inducible, eukaryotic gene expression system based on the quorum-sensing transcription factor TraR (EMBO reports, February 2003) (Erratum)

le Neddermann, Petra, Gargioli, Cesare, Muraglia, Ester, Sambucini, Sonia, Bonelli, Fabio, De Francesco, Raffaele, Cortese, Riccardo
Foilsithe 2003

Oxysterol-Binding Protein is a Phosphatidylinositol 4-kinase Effector Required for HCV Replication Membrane Integrity and Cholesterol Trafficking

le WANG, HONGLIANG, PERRY, JEFFREY W., LAURING, ADAM S., NEDDERMANN, PETRA, DE FRANCESCO, RAFFAELE, TAI, ANDREW W.
Foilsithe 2014

The Enigmatic Role of Viruses in Multiple Sclerosis: Molecular Mimicry or Disturbed Immune Surveillance?

le Geginat, Jens, Paroni, Moira, Pagani, Massimiliano, Galimberti, Daniela, De Francesco, Raffaele, Scarpini, Elio, Abrignani, Sergio
Foilsithe in Trends Immunol (2017)

The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA

le Vannini, Alessandro, Volpari, Cinzia, Gargioli, Cesare, Muraglia, Ester, Cortese, Riccardo, De Francesco, Raffaele, Neddermann, Petra, Di Marco, Stefania
Foilsithe 2002

Reduction of Hepatitis C Virus NS5A Hyperphosphorylation by Selective Inhibition of Cellular Kinases Activates Viral RNA Replication in Cell Culture

le Neddermann, Petra, Quintavalle, Manuela, Di Pietro, Chiara, Clementi, Angelica, Cerretani, Mauro, Altamura, Sergio, Bartholomew, Linda, De Francesco, Raffaele
Foilsithe 2004

Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus

le Bressanelli, Stéphane, Tomei, Licia, Roussel, Alain, Incitti, Ilario, Vitale, Rosa Letizia, Mathieu, Magali, De Francesco, Raffaele, Rey, Félix A.
Foilsithe 1999

Selection of Functional Variants of the NS3-NS4A Protease of Hepatitis C Virus by Using Chimeric Sindbis Viruses

le Filocamo, Gessica, Pacini, Laura, Nardi, Chiara, Bartholomew, Linda, Scaturro, Maria, Delmastro, Paola, Tramontano, Anna, De Francesco, Raffaele, Migliaccio, Giovanni
Foilsithe 1999

Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8–substrate complex

le Vannini, Alessandro, Volpari, Cinzia, Gallinari, Paola, Jones, Philip, Mattu, Marco, Carfí, Andrea, De Francesco, Raffaele, Steinkühler, Christian, Di Marco, Stefania
Foilsithe 2007

Metabolism of Phosphatidylinositol 4-Kinase IIIα-Dependent PI4P Is Subverted by HCV and Is Targeted by a 4-Anilino Quinazoline with Antiviral Activity

le Bianco, Annalisa, Reghellin, Veronica, Donnici, Lorena, Fenu, Simone, Alvarez, Reinaldo, Baruffa, Chiara, Peri, Francesco, Pagani, Massimiliano, Abrignani, Sergio, Neddermann, Petra, De Francesco, Raffaele
Foilsithe 2012

Cirrhosis and Rapid Virological Response to Peginterferon Plus Ribavirin Determine Treatment Outcome in HCV-1 IL28B rs12979860 CC Patients

le Aghemo, Alessio, Degasperi, Elisabetta, Rumi, Maria Grazia, Galmozzi, Enrico, Valenti, Luca, De Francesco, Raffaele, De Nicola, Stella, Cheroni, Cristina, Grassi, Eleonora, Colombo, Massimo
Foilsithe 2013

NS5A inhibitors unmask differences in functional replicase complex half-life between different hepatitis C virus strains

le Benzine, Tiffany, Brandt, Ryan, Lovell, William C., Yamane, Daisuke, Neddermann, Petra, De Francesco, Raffaele, Lemon, Stanley M., Perelson, Alan S., Ke, Ruian, McGivern, David R.
Foilsithe in PLoS Pathog (2017)

In Vitro Selection and Characterization of Hepatitis C Virus Serine Protease Variants Resistant to an Active-Site Peptide Inhibitor

le Trozzi, Caterina, Bartholomew, Linda, Ceccacci, Alessandra, Biasiol, Gabriella, Pacini, Laura, Altamura, Sergio, Narjes, Frank, Muraglia, Ester, Paonessa, Giacomo, Koch, Uwe, De Francesco, Raffaele, Steinkuhler, Christian, Migliaccio, Giovanni
Foilsithe 2003