Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function

par van Heek, Margaret, Farley, Constance, Compton, Douglas S, Hoos, Lizbeth, Davis, Harry R
Publié 2001

Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats

par van Heek, Margaret, Farley, Constance, Compton, Douglas S, Hoos, Lizbeth M, Smith-Torhan, April, Davis, Harry R
Publié 2003

Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663

par van Heek, Margaret, Farley, Constance, Compton, Douglas S, Hoos, Lizbeth, Alton, Kevin B, Sybertz, Edmund J, Davis, Harry R
Publié 2000

Atorvastatin increases intestinal expression of NPC1L1 in hyperlipidemic men

par Tremblay, André J., Lamarche, Benoît, Lemelin, Valéry, Hoos, Lizbeth, Benjannet, Suzanne, Seidah, Nabil G., Davis, Harry R., Couture, Patrick
Publié 2011

Lack of FFAR1/GPR40 Does Not Protect Mice From High-Fat Diet–Induced Metabolic Disease

par Lan, Hong, Hoos, Lizbeth M., Liu, Li, Tetzloff, Glen, Hu, Weiwen, Abbondanzo, Susan J., Vassileva, Galya, Gustafson, Eric L., Hedrick, Joseph A., Davis, Harry R.
Publié 2008

Targeted deletion of Gpbar1 protects mice from cholesterol gallstone formation

par Vassileva, Galya, Golovko, Andrei, Markowitz, Lisa, Abbondanzo, Susan J., Zeng, Ming, Yang, Shijun, Hoos, Lizbeth, Tetzloff, Glen, Levitan, Diane, Murgolo, Nicholas J., Keane, Kevin, Davis, Harry R., Hedrick, Joseph, Gustafson, Eric L.
Publié 2006

Natural Progression of Atherosclerosis from Pathologic Intimal Thickening to Late Fibroatheroma in Human Coronary Arteries: A Pathology Study

par Otsuka, Fumiyuki, Kramer, Miranda C.A., Woudstra, Pier, Yahagi, Kazuyuki, Ladich, Elena, Finn, Aloke V., de Winter, Robbert J., Kolodgie, Frank D., Wight, Thomas N., Davis, Harry R., Joner, Michael, Virmani, Renu
Publié dans Atherosclerosis (2015)

Improved efficacy for ezetimibe and rosuvastatin by attenuating the induction of PCSK9

par Ason, Brandon, Tep, Samnang, Davis, Harry R., Xu, Yiming, Tetzloff, Glen, Galinski, Beverly, Soriano, Ferdie, Dubinina, Natalya, Zhu, Lei, Stefanni, Alice, Wong, Kenny K., Tadin-Strapps, Marija, Bartz, Steven R., Hubbard, Brian, Ranalletta, Mollie, Sachs, Alan B., Flanagan, W. Michael, Strack, Alison, Kuklin, Nelly A.
Publié 2011

CDKN2B Regulates TGFβ Signaling and Smooth Muscle Cell Investment of Hypoxic Neovessels

par Nanda, Vivek, Downing, Kelly P., Ye, Jianqin, Xiao, Sophia, Kojima, Yoko, Spin, Joshua M., DiRenzo, Daniel, Nead, Kevin T., Connolly, Andrew J, Dandona, Sonny, Perisic, Ljubica, Hedin, Ulf, Maegdefessel, Lars, Dalman, Jessie, Guo, Liang, Zhao, XiaoQing, Kolodgie, Frank D., Virmani, Renu, Davis, Harry R., Leeper, Nicholas J.
Publié dans Circ Res (2015)

Glucagon receptor antagonism induces increased cholesterol absorption

par Guan, Hong-Ping, Yang, Xiaodong, Lu, Ku, Wang, Sheng-Ping, Castro-Perez, Jose M., Previs, Stephen, Wright, Michael, Shah, Vinit, Herath, Kithsiri, Xie, Dan, Szeto, Daphne, Forrest, Gail, Xiao, Jing Chen, Palyha, Oksana, Sun, Li-Ping, Andryuk, Paula J., Engel, Samuel S., Xiong, Yusheng, Lin, Songnian, Kelley, David E., Erion, Mark D., Davis, Harry R., Wang, Liangsu
Publié dans J Lipid Res (2015)

Progress and perspectives in plant sterol and plant stanol research

par Jones, Peter J H, Shamloo, Maryam, MacKay, Dylan S, Rideout, Todd C, Myrie, Semone B, Plat, Jogchum, Roullet, Jean-Baptiste, Baer, David J, Calkins, Kara L, Davis, Harry R, Barton Duell, P, Ginsberg, Henry, Gylling, Helena, Jenkins, David, Lütjohann, Dieter, Moghadasian, Mohammad, Moreau, Robert A, Mymin, David, Ostlund, Richard E, Ras, Rouyanne T, Ochoa Reparaz, Javier, Trautwein, Elke A, Turley, Stephen, Vanmierlo, Tim, Weingärtner, Oliver
Publié dans Nutr Rev (2018)

The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1)

par Garcia-Calvo, Margarita, Lisnock, JeanMarie, Bull, Herbert G., Hawes, Brian E., Burnett, Duane A., Braun, Matthew P., Crona, James H., Davis, Harry R., Dean, Dennis C., Detmers, Patricia A., Graziano, Michael P., Hughes, Meredith, MacIntyre, D. Euan, Ogawa, Anthony, O'Neill, Kim A., Iyer, Sai Prasad N., Shevell, Diane E., Smith, Marsha M., Tang, Yui S., Makarewicz, Amanda M., Ujjainwalla, Feroze, Altmann, Scott W., Chapman, Kevin T., Thornberry, Nancy A.
Publié 2005