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Glucagon receptor antagonism induces increased cholesterol absorption
Glucagon and insulin have opposing action in governing glucose homeostasis. In type 2 diabetes mellitus (T2DM), plasma glucagon is characteristically elevated, contributing to increased gluconeogenesis and hyperglycemia. Therefore, glucagon receptor (GCGR) antagonism has been proposed as a pharmacol...
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| Publicado no: | J Lipid Res |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4617405/ https://ncbi.nlm.nih.gov/pubmed/26373568 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M060897 |
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