Glucagon Receptor Antagonism Ameliorates Progression of Heart Failure

Mice were treated with a fully human monoclonal glucagon receptor antagonistic antibody REMD2.59 following myocardial infarction or pressure overload. REMD2.59 treatment blunted cardiac hypertrophy and fibrotic remodeling, and attenuated contractile dysfunction at 4 weeks after myocardial infarction...

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Detaylı Bibliyografya
Yayımlandı:JACC Basic Transl Sci
Asıl Yazarlar: Gao, Chen, Ren, Shuxun Vincent, Yu, Junyi, Baal, Ulysis, Thai, Dung, Lu, John, Zeng, Chunyu, Yan, Hai, Wang, Yibin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2019
Konular:
PRECLINICAL RESEARCH
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6488764/
https://ncbi.nlm.nih.gov/pubmed/31061918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.11.001
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