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Glucagon Receptor Antagonism Ameliorates Progression of Heart Failure
Mice were treated with a fully human monoclonal glucagon receptor antagonistic antibody REMD2.59 following myocardial infarction or pressure overload. REMD2.59 treatment blunted cardiac hypertrophy and fibrotic remodeling, and attenuated contractile dysfunction at 4 weeks after myocardial infarction...
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| Publicado no: | JACC Basic Transl Sci |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6488764/ https://ncbi.nlm.nih.gov/pubmed/31061918 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2018.11.001 |
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