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Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function

1. Ezetimibe potently inhibits the transport of cholesterol across the intestinal wall, thereby reducing plasma cholesterol in preclinical animal models of hypercholesterolemia. The effect of ezetimibe on known absorptive processes was determined in the present studies. 2. Experiments were conducted...

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Autori principali: van Heek, Margaret, Farley, Constance, Compton, Douglas S, Hoos, Lizbeth, Davis, Harry R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572957/
https://ncbi.nlm.nih.gov/pubmed/11564660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704260
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