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Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function

1. Ezetimibe potently inhibits the transport of cholesterol across the intestinal wall, thereby reducing plasma cholesterol in preclinical animal models of hypercholesterolemia. The effect of ezetimibe on known absorptive processes was determined in the present studies. 2. Experiments were conducted...

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Detalhes bibliográficos
Main Authors: van Heek, Margaret, Farley, Constance, Compton, Douglas S, Hoos, Lizbeth, Davis, Harry R
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1572957/
https://ncbi.nlm.nih.gov/pubmed/11564660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704260
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