Ensemble versus single-molecule protein unfolding

le Day, Ryan, Daggett, Valerie
Foilsithe 2005

Direct observation of microscopic reversibility in single-molecule protein folding

le Day, Ryan, Daggett, Valerie
Foilsithe 2006

Sensitivity of the folding/unfolding transition state ensemble of chymotrypsin inhibitor 2 to changes in temperature and solvent

le Day, Ryan, Daggett, Valerie
Foilsithe 2005

Four Human Thiopurine S-Methyltransferase Alleles Severely Affect Protein Structure and Dynamics

le Rutherford, Karen, Daggett, Valerie
Foilsithe 2008

The V119I polymorphism in protein L-isoaspartate O-methyltransferase alters the substrate-binding interface

le Rutherford, Karen, Daggett, Valerie
Foilsithe 2009

A Hotspot of Inactivation: The A22S and V108M Polymorphisms Individually Destabilize the Active Site Structure of Catechol O-Methyltransferase

le Rutherford, Karen, Daggett, Valerie
Foilsithe 2009

Polymorphisms and Disease: Hotspots of Inactivation in Methyltransferases

le Rutherford, Karen, Daggett, Valerie
Foilsithe 2010

Structural effects of the L145Q, V157F, and R282W cancer-associated mutations in the p53 DNA-binding core domain

le Calhoun, Sara, Daggett, Valerie
Foilsithe 2011

Analyzing Disease-Associated Protein Structures with Visual Analytics

le Bromley, Dennis, Daggett, Valerie
Foilsithe 2013

USING SIMULATIONS TO PROVIDE THE FRAMEWORK FOR EXPERIMENTAL PROTEIN FOLDING STUDIES

le Rizzuti, Bruno, Daggett, Valerie
Foilsithe 2012

De novo designed alpha-sheet peptides inhibit functional amyloid formation of Streptococcus mutans biofilms

le Paranjapye, Natasha, Daggett, Valerie
Foilsithe in J Mol Biol (2018)

Tumorigenic p53 mutants undergo common structural disruptions including conversion to α‐sheet structure

le Bromley, Dennis, Daggett, Valerie
Foilsithe in Protein Sci (2020)

The molecular basis for the chemical denaturation of proteins by urea

le Bennion, Brian J., Daggett, Valerie
Foilsithe 2003

Counteraction of urea-induced protein denaturation by trimethylamine N-oxide: A chemical chaperone at atomic resolution

le Bennion, Brian J., Daggett, Valerie
Foilsithe 2004

Dynameomics: Large-scale assessment of native protein flexibility

le Benson, Noah C., Daggett, Valerie
Foilsithe 2008

Molecular Basis for the Structural Instability of Human DJ-1 Induced by the L166P Mutation Associated with Parkinson’s Disease

le Anderson, Peter C., Daggett, Valerie
Foilsithe 2008

The R46Q, R131Q and R154H Polymorphs of Human DNA Glycosylase/β-Lyase hOgg1 Severely Distort the Active Site and DNA Recognition Site but do not Cause Unfolding

le Anderson, Peter C., Daggett, Valerie
Foilsithe 2009

The relationship between water bridges and the polyproline II conformation: a large-scale analysis of molecular dynamics simulations and crystal structures

le Law, Peter B., Daggett, Valerie
Foilsithe 2010

Protein folds and protein folding

le Schaeffer, R. Dustin, Daggett, Valerie
Foilsithe 2011

The dynameomics rotamer library: Amino acid side chain conformations and dynamics from comprehensive molecular dynamics simulations in water

le Scouras, Alexander D, Daggett, Valerie
Foilsithe 2011