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Ensemble versus single-molecule protein unfolding
Molecular dynamics (MD) simulations are the classic single-molecule “experiments,” providing atomic-resolution structural and dynamic information. However, the single-molecule nature of the technique has also been its shortcoming, with frequent criticisms of sampling inadequacies and questions regar...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2005
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1224615/ https://ncbi.nlm.nih.gov/pubmed/16155127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501773102 |
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