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Ensemble versus single-molecule protein unfolding

Molecular dynamics (MD) simulations are the classic single-molecule “experiments,” providing atomic-resolution structural and dynamic information. However, the single-molecule nature of the technique has also been its shortcoming, with frequent criticisms of sampling inadequacies and questions regar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Day, Ryan, Daggett, Valerie
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1224615/
https://ncbi.nlm.nih.gov/pubmed/16155127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0501773102
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