Hepatocellular carcinoma: a systems biology perspective

Por D'Alessandro, Lorenza A., Meyer, René, Klingmüller, Ursula
Publicado em 2013

T160-phosphorylated CDK2 defines threshold for HGF-dependent proliferation in primary hepatocytes

Por Mueller, Stephanie, Huard, Jérémy, Waldow, Katharina, Huang, Xiaoyun, D'Alessandro, Lorenza A, Bohl, Sebastian, Börner, Kathleen, Grimm, Dirk, Klamt, Steffen, Klingmüller, Ursula, Schilling, Marcel
Publicado no Mol Syst Biol (2015)

A Systems Biology Study on NFκB Signaling in Primary Mouse Hepatocytes

Por Pinna, Federico, Sahle, Sven, Beuke, Katharina, Bissinger, Michaela, Tuncay, Selcan, D’Alessandro, Lorenza A., Gauges, Ralph, Raue, Andreas, Timmer, Jens, Klingmüller, Ursula, Schirmacher, Peter, Kummer, Ursula, Breuhahn, Kai
Publicado em 2012

Disentangling the Complexity of HGF Signaling by Combining Qualitative and Quantitative Modeling

Por D’Alessandro, Lorenza A., Samaga, Regina, Maiwald, Tim, Rho, Seong-Hwan, Bonefas, Sandra, Raue, Andreas, Iwamoto, Nao, Kienast, Alexandra, Waldow, Katharina, Meyer, Rene, Schilling, Marcel, Timmer, Jens, Klamt, Steffen, Klingmüller, Ursula
Publicado no PLoS Comput Biol (2015)

Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration

Por Meyer, René, D'Alessandro, Lorenza A., Kar, Sandip, Kramer, Bernhard, She, Bin, Kaschek, Daniel, Hahn, Bettina, Wrangborg, David, Karlsson, Johan, Kvarnström, Mats, Jirstrand, Mats, Lehmann, Wolf-Dieter, Timmer, Jens, Höfer, Thomas, Klingmüller, Ursula
Publicado em 2012

The liver-specific microRNA miR-122 controls systemic iron homeostasis in mice

Por Castoldi, Mirco, Vujic Spasic, Maja, Altamura, Sandro, Elmén, Joacim, Lindow, Morten, Kiss, Judit, Stolte, Jens, Sparla, Richard, D’Alessandro, Lorenza A., Klingmüller, Ursula, Fleming, Robert E., Longerich, Thomas, Gröne, Hermann J., Benes, Vladimir, Kauppinen, Sakari, Hentze, Matthias W., Muckenthaler, Martina U.
Publicado em 2011

Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling

Por Mleczko-Sanecka, Katarzyna, Roche, Franziska, Rita da Silva, Ana, Call, Debora, D’Alessio, Flavia, Ragab, Anan, Lapinski, Philip E., Ummanni, Ramesh, Korf, Ulrike, Oakes, Christopher, Damm, Georg, D’Alessandro, Lorenza A., Klingmüller, Ursula, King, Philip D., Boutros, Michael, Hentze, Matthias W., Muckenthaler, Martina U.
Publicado em 2014

Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib

Por Sobotta, Svantje, Raue, Andreas, Huang, Xiaoyun, Vanlier, Joep, Jünger, Anja, Bohl, Sebastian, Albrecht, Ute, Hahnel, Maximilian J., Wolf, Stephanie, Mueller, Nikola S., D'Alessandro, Lorenza A., Mueller-Bohl, Stephanie, Boehm, Martin E., Lucarelli, Philippe, Bonefas, Sandra, Damm, Georg, Seehofer, Daniel, Lehmann, Wolf D., Rose-John, Stefan, van der Hoeven, Frank, Gretz, Norbert, Theis, Fabian J., Ehlting, Christian, Bode, Johannes G., Timmer, Jens, Schilling, Marcel, Klingmüller, Ursula
Publicado no Front Physiol (2017)