Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling

The hepatic hormone hepcidin is a key regulator of systemic iron metabolism. Its expression is largely regulated by 2 signaling pathways: the “iron-regulated” bone morphogenetic protein (BMP) and the inflammatory JAK-STAT pathways. To obtain broader insights into cellular processes that modulate hep...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mleczko-Sanecka, Katarzyna, Roche, Franziska, Rita da Silva, Ana, Call, Debora, D’Alessio, Flavia, Ragab, Anan, Lapinski, Philip E., Ummanni, Ramesh, Korf, Ulrike, Oakes, Christopher, Damm, Georg, D’Alessandro, Lorenza A., Klingmüller, Ursula, King, Philip D., Boutros, Michael, Hentze, Matthias W., Muckenthaler, Martina U.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2014
Assuntos:
Red Cells, Iron, and Erythropoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3945866/
https://ncbi.nlm.nih.gov/pubmed/24385536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-07-515957
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados